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韩国化学物致癌暴露的发展:韩国职业性致癌原监测系统的一项举措。

Development of Korean CARcinogen EXposure: An Initiative of the Occupational Carcinogen Surveillance System in Korea.

机构信息

Department of Occupational and Environmental Medicine, International St. Mary's Hospital, Catholic Kwandong University, Incheon, Korea.

Department of Statistics, Dongguk University, Seoul, Korea.

出版信息

Ann Work Expo Health. 2021 Jun 12;65(5):528-538. doi: 10.1093/annweh/wxaa135.

DOI:10.1093/annweh/wxaa135
PMID:33528514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8323866/
Abstract

OBJECTIVE

To prevent occupational cancers, carcinogen exposure surveillance systems have been developed in many countries. This study aimed to develop a carcinogen exposure database specific to South Korea.

METHODS

Twenty known human carcinogens were selected for this study. The International Standard Classification of Industry was used for a classification scheme of industries. Three nationwide occupational exposure databases, the Work Environment Measurement Database, the Special Health Examination Database, and the Work Environment Condition Survey, were used to calculate reference exposure prevalence estimates by carcinogen and industry. Then, 37 professional industrial hygienists with at least 19 years of field experience provided their own exposure prevalence estimates, after reviewing the abovementioned reference estimates derived from three data sources. The median value of the experts' estimates was used as the final exposure prevalence. Finally, the number of exposed workers was computed by multiplying the final exposure prevalence by the number of workers extracted from the 2010 national census data by carcinogen and industry.

RESULTS

The exposure prevalence and the number of exposed workers were calculated according to 20 carcinogen and 228 minor industrial groups, assuming year 2010 circumstances. The largest population was exposed to welding fumes (326 822 workers), followed by ultraviolet radiation (238 937 workers), ionizing radiation (168 712 workers), and mineral oil mist (146 798 workers).

CONCLUSIONS

Our results provide critical data on carcinogen exposure for the prevention of occupational cancers.

摘要

目的

为了预防职业癌症,许多国家都建立了致癌物暴露监测系统。本研究旨在开发一个特定于韩国的致癌物暴露数据库。

方法

选择了 20 种已知的人类致癌物进行本研究。国际标准产业分类被用于行业分类方案。使用了三个全国性的职业暴露数据库,即工作环境测量数据库、特殊健康检查数据库和工作环境状况调查,来计算按致癌物和行业分类的参考暴露流行率估计值。然后,37 名具有至少 19 年现场经验的专业工业卫生学家在审查了来自三个数据源的上述参考估计值后,提供了他们自己的暴露流行率估计值。专家估计值的中位数被用作最终暴露流行率。最后,通过将最终暴露流行率乘以从 2010 年全国人口普查数据中按致癌物和行业提取的工人数量,计算出暴露工人的数量。

结果

根据 20 种致癌物和 228 个小工业组,假设 2010 年的情况,计算了暴露流行率和暴露工人的数量。最大的人群暴露于焊接烟尘(326822 名工人),其次是紫外线辐射(238937 名工人)、电离辐射(168712 名工人)和矿物油雾(146798 名工人)。

结论

我们的结果提供了关于致癌物暴露的关键数据,以预防职业癌症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4047/8323866/1046aa916ece/wxaa135_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4047/8323866/1046aa916ece/wxaa135_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4047/8323866/1046aa916ece/wxaa135_fig1.jpg

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