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Phages as immunomodulators and their promising use as anti-inflammatory agents in a cftr loss-of-function zebrafish model.噬菌体作为免疫调节剂及其在 cftr 功能丧失的斑马鱼模型中作为抗炎剂的应用前景。
J Cyst Fibros. 2021 Nov;20(6):1046-1052. doi: 10.1016/j.jcf.2020.11.017. Epub 2020 Dec 6.
2
Human β-defensin-2 suppresses key features of asthma in murine models of allergic airways disease.人β-防御素-2在过敏性气道疾病小鼠模型中抑制哮喘的关键特征。
Clin Exp Allergy. 2021 Jan;51(1):120-131. doi: 10.1111/cea.13766. Epub 2020 Nov 11.
3
N-acetyl-cysteine mediates protection against Mycobacterium avium through induction of human β-defensin-2 in a mouse lung infection model.N-乙酰半胱氨酸通过诱导人β防御素-2在小鼠肺部感染模型中介导对鸟分枝杆菌的保护作用。
Microbes Infect. 2020 Nov-Dec;22(10):567-575. doi: 10.1016/j.micinf.2020.08.003. Epub 2020 Sep 1.
4
The Dichotomous Responses Driven by β-Defensins.β-防御素驱动的二分反应。
Front Immunol. 2020 Jun 12;11:1176. doi: 10.3389/fimmu.2020.01176. eCollection 2020.
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The Antimicrobial Peptide Human Beta-Defensin 2 Inhibits Biofilm Production of Without Compromising Metabolic Activity.抗菌肽人β-防御素 2 抑制 生物膜的产生而不影响代谢活性。
Front Immunol. 2020 May 8;11:805. doi: 10.3389/fimmu.2020.00805. eCollection 2020.
6
Pathogenesis of COVID-19 from a cell biology perspective.从细胞生物学角度看 COVID-19 的发病机制。
Eur Respir J. 2020 Apr 16;55(4). doi: 10.1183/13993003.00607-2020. Print 2020 Apr.
7
Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis.人 β-防御素 2 介导的免疫调节作为实验性结肠炎的治疗方法。
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Liver sinusoidal endothelial cells contribute to the uptake and degradation of entero bacterial viruses.肝窦内皮细胞有助于肠细菌病毒的摄取和降解。
Sci Rep. 2020 Jan 21;10(1):898. doi: 10.1038/s41598-020-57652-0.
9
Phage-specific diverse effects of bacterial viruses on the immune system.噬菌体对免疫系统的特异性多样影响。
Future Microbiol. 2019 Sep;14(14):1171-1174. doi: 10.2217/fmb-2019-0222. Epub 2019 Sep 19.
10
Phage Therapy of Pneumonia Is Not Associated with an Overstimulation of the Inflammatory Response Compared to Antibiotic Treatment in Mice.噬菌体治疗肺炎与抗生素治疗相比不会引起小鼠炎症反应过度。
Antimicrob Agents Chemother. 2019 Jul 25;63(8). doi: 10.1128/AAC.00379-19. Print 2019 Aug.

Bacteriophage Interactions With Epithelial Cells: Therapeutic Implications.

作者信息

Górski Andrzej, Borysowski Jan, Miȩdzybrodzki Ryszard

机构信息

Bacteriophage Laboratory, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences (HIIET PAS), Wrocław, Poland.

Phage Therapy Unit, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences (HIIET PAS), Wrocław, Poland.

出版信息

Front Microbiol. 2021 Jan 18;11:631161. doi: 10.3389/fmicb.2020.631161. eCollection 2020.

DOI:10.3389/fmicb.2020.631161
PMID:33537024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7848012/
Abstract
摘要