Beijing Luhe Hospital, Capital Medical University, Tongzhou, Beijing.
The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei province, China.
Medicine (Baltimore). 2021 Jan 22;100(3):e24104. doi: 10.1097/MD.0000000000024104.
Common bile duct stone (CBDS) is typically manifested with abdominal pain, chills, fever, and jaundice. Laparoscopic transcystic common bile duct exploration (LTCBDE) and endoscopic sphincterotomy (EST) are currently the main minimally invasive methods for the treatment of CBDS. However, there are few studies about the differences of medium and long-term complication after EST or LTCBDE. Therefore, we will conduct a meta-analysis and systematic review to systematically evaluate the difference of medium and long-term complications between EST and LTCBDE against CBDS.
Randomized controlled trials of EST or LTCBDE against CBDS will be searched in several English and Chinese databases with the following vocabularies: "laparoscopic transcystic common bile duct exploration," "endoscopic sphincterotomy," "choledocholithiasis," "common bile duct stone" until December, 2020. Two reviewers will independently conduct the literature extraction, risk of bias assessment, and statistical analysis.
The study will help to systematically evaluate the difference of medium and long-term complication between EST and LTCBDE against CBDS.
DOI 10.17605/OSF.IO/5U7SA.
胆总管结石（CBDS）的典型表现为腹痛、寒战、发热和黄疸。腹腔镜经胆囊管胆总管探查术（LTCBDE）和内镜下括约肌切开术（EST）是目前治疗 CBDS 的主要微创方法。然而，关于 EST 或 LTCBDE 后中远期并发症的差异研究较少。因此，我们将进行荟萃分析和系统评价，以系统评估 EST 和 LTCBDE 治疗 CBDS 后中远期并发症的差异。
我们将使用以下词汇在几个英文和中文数据库中搜索 EST 或 LTCBDE 治疗 CBDS 的随机对照试验：“laparoscopic transcystic common bile duct exploration”、“endoscopic sphincterotomy”、“choledocholithiasis”、“common bile duct stone”，检索时间截至 2020 年 12 月。两位评审员将独立进行文献提取、偏倚风险评估和统计分析。
该研究将有助于系统评估 EST 和 LTCBDE 治疗 CBDS 后中远期并发症的差异。
OSF 注册号：DOI 10.17605/OSF.IO/5U7SA。
