• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

自闭症早期强化行为干预的语言轨迹与治疗结果的纵向研究。

A Longitudinal Study of Language Trajectories and Treatment Outcomes of Early Intensive Behavioral Intervention for Autism.

机构信息

Center for Autism and Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

Autism Speaks, New York, NY, USA.

出版信息

J Autism Dev Disord. 2021 Dec;51(12):4534-4550. doi: 10.1007/s10803-021-04900-5. Epub 2021 Feb 8.

DOI:10.1007/s10803-021-04900-5
PMID:33559016
Abstract

The present study examined language trajectories and placement outcomes for children with autism spectrum disorder (ASD) receiving early intensive behavioral intervention (EIBI). Language measures were collected at baseline and 6, 12, 18, 24, and 36 months or until exit from EIBI in 131 children with ASD. Growth models estimated overall and subgroup language trajectories. Overall, children receiving EIBI showed substantial increases in language relative to normative expectations. Earlier age at EIBI start, higher baseline cognitive function, and lower baseline ASD severity predicted better language trajectories. Although there was significant variability in language trajectories and educational outcomes, most children showed significant increases in language scores, relative to normative expectations. Additional research, in more representative samples, is needed to understand this variability.

摘要

本研究考察了接受早期密集行为干预(EIBI)的自闭症谱系障碍(ASD)儿童的语言轨迹和安置结果。在 131 名 ASD 儿童中,在基线和 6、12、18、24 和 36 个月或直至 EIBI 退出时收集语言测量值。增长模型估计了整体和亚组的语言轨迹。总体而言,接受 EIBI 的儿童的语言相对于规范预期有了实质性的提高。EIBI 开始的年龄更早、基线认知功能更高和 ASD 严重程度更低,预示着更好的语言轨迹。尽管语言轨迹和教育结果存在显著差异,但大多数儿童的语言得分相对于规范预期有显著提高。需要在更具代表性的样本中进行更多研究,以了解这种可变性。

相似文献

1
A Longitudinal Study of Language Trajectories and Treatment Outcomes of Early Intensive Behavioral Intervention for Autism.自闭症早期强化行为干预的语言轨迹与治疗结果的纵向研究。
J Autism Dev Disord. 2021 Dec;51(12):4534-4550. doi: 10.1007/s10803-021-04900-5. Epub 2021 Feb 8.
2
Comparing the 1-year impact of preschool autism intervention programs in two Canadian provinces.比较加拿大两个省份的学前自闭症干预项目对 1 年的影响。
Autism Res. 2019 Apr;12(4):667-681. doi: 10.1002/aur.2072. Epub 2019 Jan 10.
3
Quality of Early Intensive Behavioral Intervention as a Predictor of Children's Outcome.早期强化行为干预的质量对儿童结局的预测作用。
Behav Modif. 2021 Nov;45(6):911-928. doi: 10.1177/0145445520923998. Epub 2020 May 21.
4
Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD).针对患有自闭症谱系障碍(ASD)幼儿的早期强化行为干预(EIBI)。
Cochrane Database Syst Rev. 2012 Oct 17;10:CD009260. doi: 10.1002/14651858.CD009260.pub2.
5
Sustainability of Early Intensive Behavioral Intervention for Children With Autism Spectrum Disorder in a Community Setting.社区环境中自闭症谱系障碍儿童早期强化行为干预的可持续性。
Behav Modif. 2020 Jan;44(1):3-26. doi: 10.1177/0145445518786463. Epub 2018 Jul 16.
6
Delay to Early Intensive Behavioral Intervention and Educational Outcomes for a Medicaid-Enrolled Cohort of Children with Autism.延迟早期强化行为干预对参加医疗补助计划的自闭症儿童队列的教育结果的影响。
J Autism Dev Disord. 2021 Apr;51(4):1054-1066. doi: 10.1007/s10803-020-04586-1.
7
Comparative efficacy of family mediated intervention versus early intensive behavioural intervention on symptom domains in children with autism spectrum disorder: A randomized controlled trial.家庭介导干预与早期强化行为干预对自闭症谱系障碍儿童症状领域的比较疗效:一项随机对照试验。
Asian J Psychiatr. 2024 Jun;96:104052. doi: 10.1016/j.ajp.2024.104052. Epub 2024 Apr 16.
8
Allegiance and knowledge levels of professionals working with early intensive behavioural intervention in autism.从事自闭症早期强化行为干预的专业人员的忠诚度和知识水平。
Early Interv Psychiatry. 2017 Oct;11(5):444-450. doi: 10.1111/eip.12335. Epub 2016 Apr 6.
9
A two-year prospective follow-up study of community-based early intensive behavioural intervention and specialist nursery provision for children with autism spectrum disorders.一项针对自闭症谱系障碍儿童的社区早期强化行为干预和专业托儿所服务的为期两年的前瞻性随访研究。
J Child Psychol Psychiatry. 2007 Aug;48(8):803-12. doi: 10.1111/j.1469-7610.2007.01756.x.
10
Assessing progress and outcome of early intensive behavioral intervention for toddlers with autism.评估自闭症幼儿早期强化行为干预的进展与效果。
Res Dev Disabil. 2014 Dec;35(12):3632-44. doi: 10.1016/j.ridd.2014.08.036. Epub 2014 Sep 20.

引用本文的文献

1
Optimal dosage of group-based organized physical activity for enhancing social abilities in autistic children: insights from a multilevel meta-analysis.基于小组的有组织体育活动对提高自闭症儿童社交能力的最佳剂量:一项多层次荟萃分析的见解
Int J Behav Nutr Phys Act. 2025 Jul 1;22(1):87. doi: 10.1186/s12966-025-01787-8.
2
Speech paired vagus nerve stimulation restores neural sound processing in a rat model of autism.言语配对迷走神经刺激可恢复自闭症大鼠模型中的神经声音处理能力。
Front Neurosci. 2025 Jun 13;19:1600024. doi: 10.3389/fnins.2025.1600024. eCollection 2025.
3
Developmental Disturbances in Animal Models of Autism Spectrum Disorder.

本文引用的文献

1
Understanding Hippocampal Development in Young Children With Autism Spectrum Disorder.了解自闭症谱系障碍儿童的海马体发育。
J Am Acad Child Adolesc Psychiatry. 2020 Sep;59(9):1069-1079. doi: 10.1016/j.jaac.2019.08.008. Epub 2019 Aug 23.
2
Reframing Optimal Outcomes in Autism.重新界定自闭症的最佳结果。
JAMA Pediatr. 2018 Aug 1;172(8):716-717. doi: 10.1001/jamapediatrics.2018.1016.
3
Predicting Receptive-Expressive Vocabulary Discrepancies in Preschool Children With Autism Spectrum Disorder.预测自闭症谱系障碍学龄前儿童的接受性-表达性词汇差异。
自闭症谱系障碍动物模型中的发育障碍
Dev Neurobiol. 2025 Jul;85(3):e22977. doi: 10.1002/dneu.22977.
4
School Placement Outcomes Following Early Intensive Behavioral Intervention in a Routine Clinical Care Setting.常规临床护理环境下早期强化行为干预后的学校安置结果。
J Autism Dev Disord. 2025 May 21. doi: 10.1007/s10803-025-06880-2.
5
Pairing tones with vagus nerve stimulation improves brain stem responses to speech in the valproic acid model of autism.声频与迷走神经刺激联合应用改善丙戊酸自闭症模型大鼠脑干对言语的反应。
J Neurophysiol. 2024 Nov 1;132(5):1426-1436. doi: 10.1152/jn.00325.2024. Epub 2024 Sep 25.
6
Using the ADDIE Model of Instructional Design to Create Programming for Comprehensive ABA Treatment.运用教学设计的ADDIE模型来创建综合性应用行为分析疗法的方案。
Behav Anal Pract. 2024 Feb 5;17(2):371-388. doi: 10.1007/s40617-024-00908-2. eCollection 2024 Jun.
7
Cognitive, behavioral and socio-communication skills as predictors of response to Early Start Denver Model: a prospective study in 32 young children with Autism Spectrum Disorder.认知、行为和社会沟通技能作为早期丹佛模式反应的预测因素:对32名自闭症谱系障碍幼儿的前瞻性研究
Front Psychiatry. 2024 May 30;15:1358419. doi: 10.3389/fpsyt.2024.1358419. eCollection 2024.
8
Using music to assist language learning in autistic children with minimal verbal language: The MAP feasibility RCT.使用音乐辅助极轻度语言自闭症儿童语言学习的研究:MAP 可行性 RCT。
Autism. 2024 Oct;28(10):2515-2533. doi: 10.1177/13623613241233804. Epub 2024 Mar 3.
9
The challenges for early intervention and its effects on the prognosis of autism spectrum disorder: a systematic review.早期干预的挑战及其对自闭症谱系障碍预后的影响:一项系统综述
Dement Neuropsychol. 2024 Feb 9;18:e20230034. doi: 10.1590/1980-5764-DN-2023-0034. eCollection 2024.
10
Development of webcam-collected and artificial-intelligence-derived social and cognitive performance measures for neurodevelopmental genetic syndromes.开发基于网络摄像头采集和人工智能的神经发育遗传综合征社会和认知表现评估方法。
Am J Med Genet C Semin Med Genet. 2023 Sep;193(3):e32058. doi: 10.1002/ajmg.c.32058. Epub 2023 Aug 3.
J Speech Lang Hear Res. 2018 Jun 19;61(6):1426-1439. doi: 10.1044/2018_JSLHR-L-17-0101.
4
Improving Functional Language and Social Motivation with a Parent-Mediated Intervention for Toddlers with Autism Spectrum Disorder.通过家长介导干预改善自闭症谱系障碍幼儿的功能性语言和社交动机
J Autism Dev Disord. 2017 Aug;47(8):2443-2458. doi: 10.1007/s10803-017-3155-8.
5
Universal Autism Screening for Toddlers: Recommendations at Odds.幼儿自闭症普遍筛查:相互矛盾的建议
J Autism Dev Disord. 2016 May;46(5):1880-2. doi: 10.1007/s10803-016-2697-5.
6
Early gross motor skills predict the subsequent development of language in children with autism spectrum disorder.早期粗大运动技能可预测自闭症谱系障碍儿童随后的语言发展。
Autism Res. 2016 Sep;9(9):993-1001. doi: 10.1002/aur.1587. Epub 2015 Dec 22.
7
The Autism Diagnostic Observation Schedule, Toddler Module: Standardized Severity Scores.《自闭症诊断观察量表,幼儿模块:标准化严重程度评分》
J Autism Dev Disord. 2015 Sep;45(9):2704-20. doi: 10.1007/s10803-015-2432-7.
8
Predicting Outcome of Community-Based Early Intensive Behavioral Intervention for Children with Autism.预测基于社区的自闭症儿童早期强化行为干预的结果。
J Abnorm Child Psychol. 2015 Oct;43(7):1271-82. doi: 10.1007/s10802-015-0002-2.
9
Naturalistic Developmental Behavioral Interventions: Empirically Validated Treatments for Autism Spectrum Disorder.自然主义发展行为干预:自闭症谱系障碍的实证验证疗法
J Autism Dev Disord. 2015 Aug;45(8):2411-28. doi: 10.1007/s10803-015-2407-8.
10
A randomized controlled trial of Pivotal Response Treatment Group for parents of children with autism.自闭症儿童家长关键性反应治疗团体的随机对照试验。
J Child Psychol Psychiatry. 2015 Aug;56(8):884-92. doi: 10.1111/jcpp.12354. Epub 2014 Oct 27.