Rose J D, Roberts G M, Williams G, Mayberry J F, Rhodes J
Department of Gastroenterology, University Hospital of Wales, Cardiff.
Gut. 1988 Mar;29(3):346-51. doi: 10.1136/gut.29.3.346.
The incidence of Crohn's disease in Cardiff between 1931 and 1985 has been examined using hospital diagnostic indices supplemented in recent years by records from clinicians, and the departments of pathology and radiology. Four hundred and seven new patients were confirmed after all notes had been reviewed. There has been a large increase from 0.18 cases/10(5) of the population per year in the 1930s to current values of 8.3/10(5)/year. The incidence continues to rise and shows an increasing proportion of patients with colorectal disease. Peak age specific incidences occur in the third and eighth decades of life.
利用医院诊断指数对1931年至1985年间加的夫克罗恩病的发病率进行了研究，近年来还补充了临床医生、病理科和放射科的记录。在查阅了所有病历后，确诊了407例新患者。发病率大幅上升，从20世纪30年代的每年0.18例/10万人口增至目前的每年8.3例/10万人口。发病率持续上升，且结直肠疾病患者的比例不断增加。特定年龄发病率高峰出现在人生的第三个和第八个十年。
