Mayberry J, Rhodes J, Hughes L E
Gut. 1979 Jul;20(7):602-8. doi: 10.1136/gut.20.7.602.
The incidence of Crohn's disease in Cardiff between 1934 and 1977 has been examined using hospital diagnostic indices and supplemented in recent years by personal records from clinicians. A total of 232 cases of Crohn's disease were confirmed after all the notes had been reviewed. There has been a large increase from 0.18/cases/10(5) of the population per year in the 1930s to 4.8 cases/10(5)/year in the 1970s. The major change in incidence is thought to be real rather than apparent and involves all forms of the disease in each age group. The recognition of Crohn's disease of the colon in recent years appears to have played a minor part in the rise in incidence.
利用医院诊断指标对1934年至1977年间加的夫克罗恩病的发病率进行了调查，并在近年来补充了临床医生的个人记录。在查阅了所有病历后，共确诊了232例克罗恩病病例。发病率从20世纪30年代的每年每10万人0.18例大幅上升到20世纪70年代的每年每10万人4.8例。发病率的主要变化被认为是真实的而非表面的，且涉及各年龄组的所有疾病形式。近年来对结肠克罗恩病的认识在发病率上升中似乎只起了很小的作用。
