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J Nat Prod. 2021 Feb 26;84(2):531-536. doi: 10.1021/acs.jnatprod.0c01034. Epub 2021 Feb 10.
The (-)--Δ-tetrahydrocannabiphorol (Δ-THCP, ) content of the inflorescence from six chemotypes, including 14 plants of distinct genotypes, and two extracts was determined quantitatively via high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). This represents the first comprehensive quantitative screening for from various chemotypes. Compound was detected in all 13 inflorescence samples originating from "(-)--Δ-tetrahydrocannabinol (Δ-THC, ) dominant" chemotypes, but was not detected in a "cannabidiol (CBD, ) dominant" chemotype. The inflorescence content of ranged approximately from 0.0023% to 0.0136% (w/w). Comprehensive inflorescence sampling was performed for each specimen investigated. A trend between inflorescence cannabinoid potency and the location of which the inflorescence was sampled on the plant was observed for the three cannabinoids tested (-). The preliminary results obtained indicate Δ-THCP () may have a higher degree of prevalence in inflorescence than previously estimated.
通过高效液相色谱-串联质谱（HPLC-MS/MS）定量测定了六种化学型（包括 14 种不同基因型的植物）和两种提取物的花序中（-）--Δ-四氢大麻酚（Δ-THCP，）的含量。这是首次对各种化学型的进行全面定量筛选。在所有源自“（-）--Δ-四氢大麻酚（Δ-THC，）占主导地位”化学型的 13 个花序样品中都检测到了化合物，但在“大麻二酚（CBD，）占主导地位”化学型中未检测到。的花序含量约为 0.0023%至 0.0136%（w/w）。对每个被调查的标本都进行了全面的花序取样。对三种测试的大麻素（-）进行了花序大麻素效价与花序取样位置之间关系的研究，观察到了一种趋势。初步结果表明，与之前的估计相比，Δ-THCP（）在花序中的出现频率可能更高。
