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利用网络内结构的迁移学习对内镜图像中新息肉图像进行分类的技术。

New polyp image classification technique using transfer learning of network-in-network structure in endoscopic images.

机构信息

Department of Biomedical Engineering, Gil Medical Center, Gachon University College of Medicine, 21, Namdong-daero 774 beon-gil, Namdong-gu, Incheon, 21565, Republic of Korea.

Division of Gastroenterology, Department of Internal Medicine, Gachon University Gil Medical Center, 21 Namdongdaero 774 beon-gil, Namdong-gu, Incheon, 21565, Republic of Korea.

出版信息

Sci Rep. 2021 Feb 11;11(1):3605. doi: 10.1038/s41598-021-83199-9.

DOI:10.1038/s41598-021-83199-9
PMID:33574394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7878472/
Abstract

While colorectal cancer is known to occur in the gastrointestinal tract. It is the third most common form of cancer of 27 major types of cancer in South Korea and worldwide. Colorectal polyps are known to increase the potential of developing colorectal cancer. Detected polyps need to be resected to reduce the risk of developing cancer. This research improved the performance of polyp classification through the fine-tuning of Network-in-Network (NIN) after applying a pre-trained model of the ImageNet database. Random shuffling is performed 20 times on 1000 colonoscopy images. Each set of data are divided into 800 images of training data and 200 images of test data. An accuracy evaluation is performed on 200 images of test data in 20 experiments. Three compared methods were constructed from AlexNet by transferring the weights trained by three different state-of-the-art databases. A normal AlexNet based method without transfer learning was also compared. The accuracy of the proposed method was higher in statistical significance than the accuracy of four other state-of-the-art methods, and showed an 18.9% improvement over the normal AlexNet based method. The area under the curve was approximately 0.930 ± 0.020, and the recall rate was 0.929 ± 0.029. An automatic algorithm can assist endoscopists in identifying polyps that are adenomatous by considering a high recall rate and accuracy. This system can enable the timely resection of polyps at an early stage.

摘要

虽然结直肠癌已知发生在胃肠道中,但它是韩国和全球 27 种主要癌症类型中第三常见的癌症形式。结直肠息肉已知会增加发展为结直肠癌的可能性。需要切除检测到的息肉,以降低癌症发展的风险。本研究通过在应用预训练的 ImageNet 数据库模型后对 Network-in-Network(NIN)进行微调,提高了息肉分类的性能。在 1000 张结肠镜图像上进行了 20 次随机洗牌。每组数据分为 800 张训练数据和 200 张测试数据。在 20 次实验中,对 200 张测试数据进行准确性评估。从 AlexNet 构建了三个通过从三个不同的最先进数据库转移训练权重的方法,还比较了一个没有转移学习的正常 AlexNet 方法。与其他四种最先进的方法相比,所提出的方法在统计上具有更高的准确性,与基于正常 AlexNet 的方法相比,准确性提高了 18.9%。曲线下面积约为 0.930±0.020,召回率为 0.929±0.029。通过考虑高召回率和准确性,自动算法可以帮助内窥镜医生识别出腺瘤性息肉。该系统可以使息肉在早期得到及时切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/68e93f179cf0/41598_2021_83199_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/b607399ff51d/41598_2021_83199_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/3a80f68d992b/41598_2021_83199_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/d2d59460b619/41598_2021_83199_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/68e93f179cf0/41598_2021_83199_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/b607399ff51d/41598_2021_83199_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/3a80f68d992b/41598_2021_83199_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/d2d59460b619/41598_2021_83199_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0f/7878472/68e93f179cf0/41598_2021_83199_Fig4_HTML.jpg

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