Aw Yong Poi Yi, Islam Fahmida, Harith Hanis Hazeera, Israf Daud Ahmad, Tan Ji Wei, Tham Chau Ling
School of Science, Monash University Malaysia, Subang Jaya, Malaysia.
Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia.
Front Pharmacol. 2021 Jan 26;11:599080. doi: 10.3389/fphar.2020.599080. eCollection 2020.
Honey has been conventionally consumed as food. However, its therapeutic properties have also gained much attention due to its application as a traditional medicine. Therapeutic properties of honey such as anti-microbial, anti-inflammatory, anti-cancer and wound healing have been widely reported. A number of interesting studies have reported the potential use of honey in the management of allergic diseases. Allergic diseases including anaphylaxis, asthma and atopic dermatitis (AD) are threatening around 20% of the world population. Although allergic reactions are somehow controllable with different drugs such as antihistamines, corticosteroids and mast cell stabilizers, modern dietary changes linked with allergic diseases have prompted studies to assess the preventive and therapeutic merits of dietary nutrients including honey. Many scientific evidences have shown that honey is able to relieve the pathological status and regulate the recruitment of inflammatory cells in cellular and animal models of allergic diseases. Clinically, a few studies demonstrated alleviation of allergic symptoms in patients after application or consumption of honey. Therefore, the objective of this mini review is to discuss the effectiveness of honey as a treatment or preventive approach for various allergic diseases. This mini review will provide insights into the potential use of honey in the management of allergic diseases in clinical settings.
蜂蜜一直以来都被当作食物食用。然而,由于其作为传统药物的应用,它的治疗特性也备受关注。蜂蜜的抗菌、抗炎、抗癌及伤口愈合等治疗特性已被广泛报道。一些有趣的研究报告了蜂蜜在过敏性疾病管理中的潜在用途。包括过敏反应、哮喘和特应性皮炎(AD)在内的过敏性疾病正威胁着全球约20%的人口。尽管过敏反应可以通过抗组胺药、皮质类固醇和肥大细胞稳定剂等不同药物在一定程度上得到控制,但与过敏性疾病相关的现代饮食变化促使人们开展研究,以评估包括蜂蜜在内的膳食营养成分的预防和治疗价值。许多科学证据表明,在过敏性疾病的细胞和动物模型中,蜂蜜能够缓解病理状态并调节炎症细胞的募集。临床上,一些研究表明,患者在使用或食用蜂蜜后,过敏症状有所减轻。因此,本综述的目的是探讨蜂蜜作为各种过敏性疾病的治疗或预防方法的有效性。本综述将深入探讨蜂蜜在临床环境中管理过敏性疾病的潜在用途。