• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

蜂产品的药学前景：特别关注其抗癌、抗菌、抗病毒和抗寄生虫特性

Pharmaceutical Prospects of Bee Products: Special Focus on Anticancer, Antibacterial, Antiviral, and Antiparasitic Properties.

作者信息

Nainu Firzan, Masyita Ayu, Bahar Muh Akbar, Raihan Muhammad, Prova Shajuthi Rahman, Mitra Saikat, Emran Talha Bin, Simal-Gandara Jesus

机构信息

Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Sulawesi Selatan, Indonesia.

Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.

出版信息

Antibiotics (Basel). 2021 Jul 6;10(7):822. doi: 10.3390/antibiotics10070822.

DOI:10.3390/antibiotics10070822
PMID:34356743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8300842/
Abstract

Bee products have long been used in traditional healing practices to treat many types of disorders, including cancer and microbial-related diseases. Indeed, several chemical compounds found in bee products have been demonstrated to display anticancer, antibacterial, antiviral, and antiparasitic properties. With the improvement of research tools and in view of recent advances related to bee products, this review aims to provide broad yet detailed insight into the pharmaceutical prospects of bee products such as honey, propolis, bee pollen, royal jelly, bee bread, beeswax, and bee venom, in the domain of cancer and infectious disease management. Available literature confirms the efficacy of these bee products in the alleviation of cancer progression, inhibition of bacterial and viral proliferation, and mitigation of parasitic-related symptoms. With such potentials, bioactive components isolated from the bee products can be used as an alternative approach in the long-run effort to improve humans' health at a personal and community level.

摘要

蜂产品长期以来一直被用于传统治疗方法中，以治疗多种疾病，包括癌症和与微生物相关的疾病。事实上，已证明蜂产品中发现的几种化合物具有抗癌、抗菌、抗病毒和抗寄生虫特性。随着研究工具的改进以及鉴于与蜂产品相关的最新进展，本综述旨在对蜂蜜、蜂胶、蜂花粉、蜂王浆、蜂粮、蜂蜡和蜂毒等蜂产品在癌症和传染病管理领域的药学前景提供广泛而详细的见解。现有文献证实了这些蜂产品在缓解癌症进展、抑制细菌和病毒增殖以及减轻寄生虫相关症状方面的功效。鉴于这些潜力，从长远来看，从蜂产品中分离出的生物活性成分可作为一种替代方法，以在个人和社区层面改善人类健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/8d2691b00794/antibiotics-10-00822-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/a1b2566f3bde/antibiotics-10-00822-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/e439c97d1b36/antibiotics-10-00822-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/e9a762f25d30/antibiotics-10-00822-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/5d19f80e3193/antibiotics-10-00822-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/be4af90184f8/antibiotics-10-00822-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/d5179ab3c567/antibiotics-10-00822-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/c533c3c8f8f7/antibiotics-10-00822-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/6f1df05afd0d/antibiotics-10-00822-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/5995eeaf905a/antibiotics-10-00822-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/df27b8cfe649/antibiotics-10-00822-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/8d2691b00794/antibiotics-10-00822-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/a1b2566f3bde/antibiotics-10-00822-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/e439c97d1b36/antibiotics-10-00822-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/e9a762f25d30/antibiotics-10-00822-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/5d19f80e3193/antibiotics-10-00822-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/be4af90184f8/antibiotics-10-00822-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/d5179ab3c567/antibiotics-10-00822-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/c533c3c8f8f7/antibiotics-10-00822-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/6f1df05afd0d/antibiotics-10-00822-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/5995eeaf905a/antibiotics-10-00822-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/df27b8cfe649/antibiotics-10-00822-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee6e/8300842/8d2691b00794/antibiotics-10-00822-g011.jpg

相似文献

1
Pharmaceutical Prospects of Bee Products: Special Focus on Anticancer, Antibacterial, Antiviral, and Antiparasitic Properties.蜂产品的药学前景：特别关注其抗癌、抗菌、抗病毒和抗寄生虫特性
Antibiotics (Basel). 2021 Jul 6;10(7):822. doi: 10.3390/antibiotics10070822.
2
General Nutritional Profile of Bee Products and Their Potential Antiviral Properties against Mammalian Viruses.蜂产品的一般营养概况及其对哺乳动物病毒的潜在抗病毒特性。
Nutrients. 2022 Aug 30;14(17):3579. doi: 10.3390/nu14173579.
3
Antiviral Activity of Bee Products.蜂产品的抗病毒活性。
Curr Pharm Des. 2022;28(35):2867-2878. doi: 10.2174/1381612828666220928110103.
4
Bee Products: An Emblematic Example of Underutilized Sources of Bioactive Compounds.蜂产品：生物活性化合物未充分利用资源的典型代表。
J Agric Food Chem. 2022 Jun 15;70(23):6833-6848. doi: 10.1021/acs.jafc.1c05822. Epub 2022 Jan 2.
5
Therapeutic Properties of Bioactive Compounds from Different Honeybee Products.不同蜂产品中生物活性化合物的治疗特性。
Front Pharmacol. 2017 Jun 28;8:412. doi: 10.3389/fphar.2017.00412. eCollection 2017.
6
Beehive Products as Antibacterial Agents: A Review.蜂箱产品作为抗菌剂：综述
Antibiotics (Basel). 2021 Jun 15;10(6):717. doi: 10.3390/antibiotics10060717.
7
Promising Antimicrobial Properties of Bioactive Compounds from Different Honeybee Products.不同蜜蜂产品中的生物活性化合物具有良好的抗菌性能。
Molecules. 2021 Jun 30;26(13):4007. doi: 10.3390/molecules26134007.
8
Applications of honeybee-derived products in bone tissue engineering.蜜蜂衍生产品在骨组织工程中的应用。
Bone Rep. 2024 Jan 19;20:101740. doi: 10.1016/j.bonr.2024.101740. eCollection 2024 Mar.
9
Bee Products in Dermatology and Skin Care.蜂产品在皮肤科和皮肤护理中的应用。
Molecules. 2020 Jan 28;25(3):556. doi: 10.3390/molecules25030556.
10
Bee-Derived Products: Chemical Composition and Applications in Skin Tissue Engineering.蜂源产品：化学成分及其在皮肤组织工程中的应用
Pharmaceutics. 2022 Mar 30;14(4):750. doi: 10.3390/pharmaceutics14040750.

引用本文的文献

1
Exploring the potential of hydro alcoholic crude extract of beeswax as antibacterial antifungal antiviral antiinflammatory and antioxidant agent.探索蜂蜡水醇粗提物作为抗菌、抗真菌、抗病毒、抗炎和抗氧化剂的潜力。
Sci Rep. 2025 Sep 12;15(1):32512. doi: 10.1038/s41598-025-17830-4.
2
Antimicrobial Potential of Bee-Derived Products: Insights into Honey, Propolis and Bee Venom.蜂源产品的抗菌潜力：对蜂蜜、蜂胶和蜂毒的见解
Pathogens. 2025 Aug 6;14(8):780. doi: 10.3390/pathogens14080780.
3
Assessing the Influence of Stimulatory Feeding of Bee Colonies on Mineral Composition and Antioxidant Activity of Bee Venom.

本文引用的文献

1
Determination of the antioxidant, antimicrobial and anticancer properties of the honey phenolic extract of five different regions of Bingöl province.宾格尔省五个不同地区蜂蜜酚类提取物的抗氧化、抗菌和抗癌特性测定
J Food Sci Technol. 2021 Jun;58(6):2420-2430. doi: 10.1007/s13197-020-04783-x. Epub 2020 Sep 22.
2
Surveillance data for human leishmaniasis indicate the need for a sustainable action plan for its management and control, Greece, 2004 to 2018.2004年至2018年希腊人体利什曼病监测数据表明，需要制定一项可持续的管理和控制行动计划。
Euro Surveill. 2021 May;26(18). doi: 10.2807/1560-7917.ES.2021.26.18.2000159.
3
评估刺激蜂群饲养对蜂毒矿物质组成和抗氧化活性的影响。
Insects. 2025 Apr 17;16(4):423. doi: 10.3390/insects16040423.
4
Changes in Ascorbic Acid, Phenolic Compound Content, and Antioxidant Activity In Vitro in Bee Pollen Depending on Storage Conditions: Impact of Drying and Freezing.不同储存条件下蜂花粉中抗坏血酸、酚类化合物含量及体外抗氧化活性的变化：干燥和冷冻的影响
Antioxidants (Basel). 2025 Apr 12;14(4):462. doi: 10.3390/antiox14040462.
5
Forecasting the Impact of Climate Change on (Fabricius, 1793) Habitat and Distribution in Pakistan.预测气候变化对（法布里丘斯，1793年）在巴基斯坦的栖息地和分布的影响。
Insects. 2025 Mar 11;16(3):289. doi: 10.3390/insects16030289.
6
Deciphering the Neuroprotective Action of Bee Venom Peptide Melittin: Insights into Mechanistic Interplay.解读蜂毒肽蜂毒素的神经保护作用：对机制相互作用的见解
Mol Neurobiol. 2025 Mar 4. doi: 10.1007/s12035-025-04808-6.
7
Therapeutic Potential of Propolis and Royal Jelly in Encephalitozoon Intestinalis Infection: An in Vitro Study.蜂胶和蜂王浆对肠道脑胞内原虫感染的治疗潜力：一项体外研究
Acta Parasitol. 2025 Jan 24;70(1):26. doi: 10.1007/s11686-024-00956-2.
8
Evaluating the antibacterial efficacy of bee venom against multidrug-resistant pathogenic bacteria: Escherichia coli, Salmonella typhimurium, and Enterococcus faecalis.评估蜂毒对多重耐药病原菌（大肠杆菌、鼠伤寒沙门氏菌和粪肠球菌）的抗菌功效。
World J Microbiol Biotechnol. 2025 Jan 16;41(2):40. doi: 10.1007/s11274-024-04248-9.
9
Bee Pollen as a Source of Biopharmaceuticals for Neurodegeneration and Cancer Research: A Scoping Review and Translational Prospects.蜂花粉作为神经退行性疾病和癌症研究的生物制药来源：一项范围综述及转化前景
Molecules. 2024 Dec 13;29(24):5893. doi: 10.3390/molecules29245893.
10
Enzyme Inhibitory, Physicochemical, and Phytochemical Properties and Botanical Sources of Honey, Bee Pollen, Bee Bread, and Propolis Obtained from the Same Apiary.从同一养蜂场获取的蜂蜜、蜂花粉、蜂粮和蜂胶的酶抑制、物理化学、植物化学特性及植物来源
Antioxidants (Basel). 2024 Dec 5;13(12):1483. doi: 10.3390/antiox13121483.
Apoptosis-mediated anticancer activity in prostate cancer cells of a chestnut honey (Castanea sativa L.) quinoline-pyrrolidine gamma-lactam alkaloid.
栗花蜂蜜（Castanea sativa L.）喹啉-吡咯烷γ-内酰胺生物碱对前列腺癌细胞的凋亡介导抗癌活性。
Amino Acids. 2021 Jun;53(6):869-880. doi: 10.1007/s00726-021-02987-9. Epub 2021 May 4.
4
In Vitro Antimicrobial, Antioxidant and Anticancer Activities of Egyptian Citrus Beebread.埃及柑橘蜂粮的体外抗菌、抗氧化和抗癌活性
Molecules. 2021 Apr 22;26(9):2433. doi: 10.3390/molecules26092433.
5
The antibacterial activities of honey.蜂蜜的抗菌活性。
Saudi J Biol Sci. 2021 Apr;28(4):2188-2196. doi: 10.1016/j.sjbs.2020.10.017. Epub 2020 Oct 16.
6
Mechanism of antimicrobial activity of honeybee (Apis mellifera) venom on Gram-negative bacteria: Escherichia coli and Pseudomonas spp.蜜蜂（意大利蜜蜂）毒液对革兰氏阴性菌大肠杆菌和假单胞菌属的抗菌活性机制
AMB Express. 2021 Apr 9;11(1):54. doi: 10.1186/s13568-021-01214-8.
7
Insights on recent approaches in drug discovery strategies and untapped drug targets against drug resistance.关于药物发现策略中近期方法以及针对耐药性的未开发药物靶点的见解。
Futur J Pharm Sci. 2021;7(1):56. doi: 10.1186/s43094-021-00196-5. Epub 2021 Mar 3.
8
Chemical characterization of Saudi propolis and its antiparasitic and anticancer properties.沙特蜂胶的化学特征及其抗寄生虫和抗癌特性。
Sci Rep. 2021 Mar 8;11(1):5390. doi: 10.1038/s41598-021-84717-5.
9
Current State and Promising Opportunities on Pharmaceutical Approaches in the Treatment of Polymicrobial Diseases.治疗多种微生物疾病的药物方法的现状与潜在机遇
Pathogens. 2021 Feb 20;10(2):245. doi: 10.3390/pathogens10020245.
10
Propolis, Bee Honey, and Their Components Protect against Coronavirus Disease 2019 (COVID-19): A Review of In Silico, In Vitro, and Clinical Studies.蜂胶、蜂蜜及其成分可预防 2019 年冠状病毒病（COVID-19）：基于计算机模拟、体外和临床研究的综述。
Molecules. 2021 Feb 25;26(5):1232. doi: 10.3390/molecules26051232.