人类多形核白细胞对细菌吞噬作用的限制因素。
Limiting factors in bacterial phagocytosis by human polymorphonuclear leukocytes.
作者信息
Björkstén B, Peterson P K, Verhoef J, Quie P G
出版信息
Acta Pathol Microbiol Scand C. 1977 Oct;85(5):345-9. doi: 10.1111/j.1699-0463.1977.tb03652.x.
Abstract
Limiting factors in neutrophil phagocytosis were studied using a sensitive assay by which attachment, ingestion and intracellular killing of bacteria could be separated. Phagocytosis was found to be limited by the attachment capacity of neutrophils. Ingestion and intracellular killing proceeded at a constant rate proportional to the number of bacteria attached to the neutrophils.
摘要
利用一种灵敏的检测方法研究了中性粒细胞吞噬作用的限制因素，通过该方法可以区分细菌的附着、摄取和细胞内杀伤。发现吞噬作用受中性粒细胞的附着能力限制。摄取和细胞内杀伤以与附着在中性粒细胞上的细菌数量成比例的恒定速率进行。
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