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制备环氧官能化聚合物的简单有效方法及其在电化学免疫传感器中的应用。

Simple and Effective Approach to Prepare an Epoxy-Functionalized Polymer and Its Application for an Electrochemical Immunosensor.

作者信息

Zhang Xiangyang, Shen Youming, Shen Guangyu, Zhang Chunxiang

机构信息

Hunan Province Cooperative Innovation Center for the Construction & Development of Dongting Lake Ecological Economic Zone, College of Chemistry and Material Engineering, Hunan University of Arts and Science, Changde 415000, P. R. China.

Hunan Provincial Key Laboratory of Water Treatment Functional Materials, Hunan Province Engineering Research Center of Electroplating Wastewater Reuse Technology, Changde 415000, P. R. China.

出版信息

ACS Omega. 2021 Jan 26;6(5):3637-3643. doi: 10.1021/acsomega.0c05183. eCollection 2021 Feb 9.

Abstract

An epoxy-functionalized polymer based on a new skeleton has been prepared via an efficient method and it combined with aminated carbon nanotubes to form a new composite material. This new composite material was applied for the fabrication of an electrochemical immunosensor with good performance. The inexpensive and easily available IgG was used to test the performance of the prepared composite material. The levels of IgG were quantitatively analyzed using a differential pulse voltammetry detection system and the lowest detection limit was calculated to be 0.05 ng/mL. The detection system can also respond to IgG in the concentration range from 0.1 to 25 ng/mL.

摘要

一种基于新骨架的环氧官能化聚合物已通过一种有效方法制备出来,并且它与胺化碳纳米管结合形成了一种新型复合材料。这种新型复合材料被应用于制造性能良好的电化学免疫传感器。使用价格低廉且易于获得的免疫球蛋白G(IgG)来测试所制备复合材料的性能。使用差分脉冲伏安检测系统对IgG水平进行定量分析,计算得出最低检测限为0.05纳克/毫升。该检测系统还能对浓度范围在0.1至25纳克/毫升的IgG作出响应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b8f/7876694/80c59e6cc2f1/ao0c05183_0010.jpg

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