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感染水稻白叶枯病菌的噬菌体Xoo-sp13的基因组分析

Genomic analysis of bacteriophage Xoo-sp13 infecting Xanthomonas oryzae pv. oryzae.

作者信息

Nazir Amina, Dong Zhaoxia, Liu Jin, Tahir Rana Adnan, Rasheed Madiha, Qing Hong, Peng Donghai, Tong Yigang

机构信息

Key Laboratory of Molecular Medicine and Biotherapy in the Ministry of Industry and Information Technology, Department of Biology, School of Life Sciences, Beijing Institute of Technology, Beijing, People's Republic of China.

State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.

出版信息

Arch Virol. 2021 Apr;166(4):1263-1265. doi: 10.1007/s00705-021-04985-4. Epub 2021 Feb 14.

Abstract

Xanthomonas oryzae pv. oryzae is a bacterial pathogen that gives rise to diseases in rice all over the world. A bacteriophage infecting this bacterium was isolated from rice fields in China. Here, we report the complete genome sequence of this phage, which has a linear dsDNA genome of 309,023 bp and a G + C content of 42.43%. It contains 401 open reading frames and encodes 28 tRNAs. It belongs to the family Myoviridae and has a broad host range, making it a possible candidate for phage therapy.

摘要

水稻白叶枯病菌是一种在全球范围内引发水稻病害的细菌病原体。从中国稻田中分离出一种感染该细菌的噬菌体。在此,我们报告该噬菌体的完整基因组序列,其线性双链DNA基因组大小为309,023 bp,G + C含量为42.43%。它包含401个开放阅读框并编码28个tRNA。它属于肌尾噬菌体科,具有广泛的宿主范围,使其成为噬菌体治疗的一个可能候选者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88b/7970823/d97b1dab9258/705_2021_4985_Fig1_HTML.jpg

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