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核桃寡肽对Z7的有益作用及机制

Beneficial effect and mechanism of walnut oligopeptide on Z7.

作者信息

Ding Ting, Li Yong

机构信息

Department of Nutrition and Food Hygiene School of Public Health Peking University Beijing China.

出版信息

Food Sci Nutr. 2021 Jan 8;9(2):672-681. doi: 10.1002/fsn3.2029. eCollection 2021 Feb.

DOI:10.1002/fsn3.2029
PMID:33598152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7866578/
Abstract

Prebiotics can stimulate the growth and activity of probiotics and have a variety of physiological functions. However, the study of walnut oligopeptides as prebiotics to promote probiotics is rarely reported. Therefore, in order to explore the beneficial effect of walnut oligopeptide (WOPs) on Z7, WOPs was added to the medium of Z7, and the utilization of WOPs, the effect of WOPs on the biofilm, extracellular polymeric substances, and bacterial death were explored. The results showed that the growth-promoting effect was strengthened with the increasing concentrations of WOPs. The content of bacterial biofilm and EPS increased significantly, and the number of dead bacteria decreased. The beneficial effect of WOPs was probably because that it enhanced the secretion of biofilm which was regulated by bacterial quorum sensing system and promoted the ability of bacteria to resist the adverse environment, thus promoting the growth and reproduction of bacteria.

摘要

益生元可以刺激益生菌的生长和活性,并具有多种生理功能。然而,关于核桃寡肽作为益生元促进益生菌生长的研究鲜有报道。因此,为了探究核桃寡肽(WOPs)对Z7的有益作用,将WOPs添加到Z7的培养基中,研究了Z7对WOPs的利用情况、WOPs对生物膜、胞外聚合物以及细菌死亡的影响。结果表明,随着WOPs浓度的增加,其促进生长的作用增强。细菌生物膜和胞外聚合物的含量显著增加,死菌数量减少。WOPs的有益作用可能是因为它增强了受细菌群体感应系统调控的生物膜分泌,提高了细菌抵抗不利环境的能力,从而促进了细菌的生长和繁殖。

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