Hamilton J W, Boisen R J, Yamamoto D T, Wagner J L, Reichelderfer M
Department of Medicine, University of Wisconsin, Madison.
Dig Dis Sci. 1988 May;33(5):518-22. doi: 10.1007/BF01798350.
In a randomized crossover study, we compared the effect on gastroesophageal reflux of three sleeping positions: elevation of the head of the bed on standard eight-inch bed blocks; elevation by a foam wedge; or a flat position. Fifteen subjects with moderate to severe reflux symptoms were studied in each position on consecutive nights using continuous intraesophageal pH monitoring. We found no difference in reflux frequency among the positions. The wedge caused a statistically significant decrease in the time that distal esophageal pH was less than 4 as compared to the flat position. The wedge also decreased the longest episode experienced by the subjects. Elevation on blocks caused a similar improvement in parameters but failed in this study to achieve statistical significance. Both elevation by a wedge and on blocks showed a trend towards a decrease in clearance time as compared to the flat position. The patients did not always prefer elevation on a wedge, but for some it is a valuable alternative to elevation by bed blocks.
在一项随机交叉研究中，我们比较了三种睡眠姿势对胃食管反流的影响：使用标准的八英寸床架将床头抬高；使用泡沫楔形物抬高；或平躺姿势。连续几晚，通过持续食管内pH监测，对15名有中度至重度反流症状的受试者在每种姿势下进行了研究。我们发现不同姿势下的反流频率没有差异。与平躺姿势相比，楔形物使食管远端pH值低于4的时间有统计学意义的下降。楔形物还减少了受试者经历的最长发作时间。使用床架抬高也使各项参数有类似改善，但在本研究中未达到统计学意义。与平躺姿势相比，使用楔形物和床架抬高都显示出清除时间有下降趋势。患者并非总是更喜欢使用楔形物抬高，但其对一些人而言是床架抬高的一个有价值的替代方法。
