Laboratory of Desalination and Natural Water Valorisation (LADVEN), Water Researches and Technologies Center (CERTE), Techno-park BorjCedria, BP 273, 8020, Soliman, Tunisia.
Valorization Laboratory of Useful Materials (LVMU), National Center of Material Science Research (CNRSM), Techno-park BorjCesdria, University of Carthage, BP 273, 8020, Soliman, Tunisia.
Mikrochim Acta. 2021 Feb 21;188(3):94. doi: 10.1007/s00604-021-04753-w.
A molecularly imprinted paper-based analytical device (MIP-μPAD) was developed for the sensing of bisphenol A (BPA). The platform was screen-printed onto a filter paper support, where the electrodes and the fluorescence μPADs were designed. Owing to its dual electrochemical and fluorescence responses, molecularly imprinted curcumin nanoparticles were used to sense BPA. The μPAD design was characterized by transmission electron microscopy, scanning electron microscopy, fluorescence spectroscopy, and electrochemical techniques. The sensor design comprised a wide linear range from 1 to 200 μg L with limits of detection of 0.47 ± 0.2 and 0.62 ± 0.3 μg L (LOD, S/N = 3) for electrochemical and fluorescence sensing, respectively. Furthermore, the system showed good analytical performance such as selectivity, stability, and reproducibility. The feasibility of the MIP-μPAD was demonstrated for the sensing of BPA in seawater, foods, and polycarbonate plastic packaged water with recovery values of 97.2 and 101.8%.
一种分子印迹纸基分析器件（MIP-μPAD）被开发用于双酚 A（BPA）的传感。该平台被丝网印刷到滤纸支撑物上，其中设计了电极和荧光 μPAD。由于其双重电化学和荧光响应，使用分子印迹姜黄素纳米粒子来感测 BPA。通过透射电子显微镜、扫描电子显微镜、荧光光谱和电化学技术对 μPAD 设计进行了表征。传感器设计包括从 1 到 200μg/L 的宽线性范围，电化学和荧光传感的检测限分别为 0.47±0.2 和 0.62±0.3μg/L（LOD，S/N=3）。此外，该系统表现出良好的分析性能，如选择性、稳定性和重现性。该 MIP-μPAD 已成功用于海水、食品和聚碳酸酯塑料包装水中 BPA 的传感，回收率为 97.2%和 101.8%。
