成人外周置入中心静脉导管相关无症状性血栓形成的发生率：系统评价和荟萃分析。

The incidence of asymptomatic thrombosis related to peripherally inserted central catheter in adults: A systematic review and meta-analysis People's.

机构信息

School of Nursing, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

Department of Emergency, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

出版信息

Nurs Open. 2021 Sep;8(5):2249-2261. doi: 10.1002/nop2.811. Epub 2021 Feb 22.

AIM

To examine the incidence and risk factors for asymptomatic peripherally inserted central catheter-related thrombosis (PICC-RT).

DESIGN

We performed a systematic review and meta-analysis following the PRISMA guidelines.

METHODS

The review was registered in PROSPERO (CRD42020186732). A systematic search of EMBASE, CINAHL, PubMed, Web of Science and Cochrane was performed from inception to 4 June 2020. Meta-analysis was performed to determine the pooled incidence of asymptomatic PICC-RT.

RESULTS

Ten studies comprising 1591 participants with 1592 PICCs were included in this meta-analysis. The pooled incidence of asymptomatic PICC-RT in adults was 22% (95% CI, 0.17-0.29). The pooled incidence of PICC-RT in cancer patients was 19% (95% CI, 0.13-0.26). Asymptomatic PICC-RT mainly occurred in superficial veins. Most asymptomatic thrombosis occurred 3-12 days after the PICC insertion. A higher Eastern Cooperative Oncology Group score (ECOG), slower blood flow velocity and left basilic vein were independent risk factors of asymptomatic thrombosis.

目的

探讨无症状经外周静脉穿刺中心静脉置管相关血栓形成（PICC-RT）的发生率及危险因素。

设计

我们按照 PRISMA 指南进行了系统评价和荟萃分析。

方法

该综述在 PROSPERO（CRD42020186732）上进行了注册。从建库至 2020 年 6 月 4 日，我们对 EMBASE、CINAHL、PubMed、Web of Science 和 Cochrane 进行了系统检索。采用荟萃分析来确定无症状 PICC-RT 的汇总发生率。

结果

纳入的 10 项研究共纳入了 1591 名参与者的 1592 例 PICC，这些研究纳入了荟萃分析。成年人无症状 PICC-RT 的汇总发生率为 22%（95%CI，0.17-0.29）。癌症患者 PICC-RT 的汇总发生率为 19%（95%CI，0.13-0.26）。无症状 PICC-RT 主要发生在浅静脉。大多数无症状血栓形成发生在 PICC 插入后 3-12 天。较高的东部合作肿瘤学组（ECOG）评分、较慢的血流速度和左侧贵要静脉是无症状血栓形成的独立危险因素。