Division of Health Care Research, Center for Public Health Sciences, National Cancer Center Japan, Tokyo, Japan.
Faculty of Bioscience and Applied Chemistry, Hosei University, Tokyo, Japan.
BMC Cancer. 2021 Feb 22;21(1):184. doi: 10.1186/s12885-021-07804-w.
To review the settings and outcomes of high-intensity interval training (HIIT) interventions for breast cancer survivors, and to explore the feasibility of prescribing exercise for breast cancer survivors.
A systematic search of electronic databases was conducted for studies published up to May 31, 2020. Eligibility criteria included randomized controlled trials of HIIT intervention in breast cancer survivors. Studies were grouped by whether the intervention was conducted during or after breast cancer treatment, and intervention methods and outcomes were reviewed within each group.
Twenty-six studies were identified, and 13 satisfied the inclusion criteria. Intervention was conducted during treatment in 8 studies, and after treatment in 5. Intervention duration ranged from 3 to 16 weeks, with 2 or 3 sessions per week, for a total of 9 to 36 sessions. All interventions were supervised; 12 were lab-based, and 1 was community-based. One of most promising outcomes was improvement of cardiorespiratory fitness by HIIT.
This review found that all studies on HIIT for breast cancer survivors investigated lab-based, supervised interventions, but not home-based or unsupervised. HIIT is a time-efficient method for increasing cardiovascular function in breast cancer survivors, but further research is necessary to determine its effects on other outcomes.
本研究旨在回顾高强度间歇训练（HIIT）干预乳腺癌幸存者的设置和结果，并探讨为乳腺癌幸存者开具运动处方的可行性。
对截至 2020 年 5 月 31 日发表的研究进行了电子数据库的系统检索。纳入标准包括 HIIT 干预乳腺癌幸存者的随机对照试验。研究按干预是在乳腺癌治疗期间还是治疗后进行分组，并在每组内回顾干预方法和结果。
共确定了 26 项研究，其中 13 项符合纳入标准。8 项研究在治疗期间进行干预，5 项在治疗后进行干预。干预持续时间从 3 周到 16 周不等，每周 2 或 3 次，共 9 至 36 次。所有干预均为监督性的；其中 12 项为实验室基础，1 项为社区基础。最有前途的结果之一是 HIIT 改善了心肺适应性。
本综述发现，所有关于乳腺癌幸存者 HIIT 的研究都调查了实验室基础、监督干预，但不包括家庭或无人监督的干预。HIIT 是提高乳腺癌幸存者心血管功能的一种高效方法，但需要进一步研究来确定其对其他结果的影响。
