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Luts-V:一种用于评估男性下尿路症状的新简化评分系统。

Luts-V: A new simplified score for assessing lower urinary tract symptoms in men.

作者信息

Silva Caroline Santos, de Araujo Ueslei Menezes, Alvaia Mateus Andrade, Freitas Kátia Santana, Tiraboschi Taciana Leonel Nunes, Gomes Cristiano Mendes, de Bessa José

机构信息

Departamento de Saúde Coletiva, Universidade Estadual de Feira de Santana, Bahia, Brasil.

Faculdade de Medicina, Universidade Estadual de Feira de Santana, Bahia, Brasil.

出版信息

Int Braz J Urol. 2021 May-Jun;47(3):525-532. doi: 10.1590/S1677-5538.IBJU.2020.0278.

DOI:10.1590/S1677-5538.IBJU.2020.0278
PMID:33620997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7993949/
Abstract

OBJECTIVES

Develop and validate a new and simplified score for evaluating the lower urinary tract symptoms in men.

MATERIALS AND METHODS

We modified the existing visual prostate symptom score, including changes in the images, sequence, and new alternatives, resulting in a new visual score (LUTS visual score-LUTS-V). For the validation of the new tool, we used the International Prostatic Symptom Score as the gold-standard and the new LUTS-V to 306 men. The total IPSS score and the total LUTS-V score of each subject were evaluated to determine the agreement between the two instruments. ROC curve was used to evaluate the diagnostic accuracy and best cut-off of LUTS-V. Sensitivity, specificity, and diagnostic odds ratios were used to describe the diagnostic properties.

RESULTS

The mean age of the participants was 59 [52-87] years. There was a significant correlation between LUTS-V and IPSS. (r=0.72 (p<0.0001). The Bland-Altman analyzes demonstrate good agreement between the two questionnaires (bias=5.6%). LUTS-V demonstrated excellent diagnostic accuracy in detecting the most serious cases with an area under the ROC curve of 83% [78-87%] 95% CI. p <0.001). LUTS-V >4 was the best threshold, with a sensitivity of 74% and specificity of 78%.

CONCLUSIONS

LUTS-V is a simple, self-administered tool with a significant discriminatory power to identify subjects with moderate to severe LUTS and may represent a useful instrument for the diagnosis and follow-up of men with urinary symptoms.

摘要

目的

开发并验证一种用于评估男性下尿路症状的新型简化评分系统。

材料与方法

我们对现有的视觉前列腺症状评分进行了修改,包括图像、顺序的改变以及新的选项,从而得到了一种新的视觉评分(下尿路症状视觉评分-LUTS-V)。为验证这一新工具,我们将国际前列腺症状评分作为金标准,并将新的LUTS-V应用于306名男性。评估每位受试者的国际前列腺症状评分总分和LUTS-V总分,以确定两种工具之间的一致性。采用ROC曲线评估LUTS-V的诊断准确性和最佳截断值。使用敏感性、特异性和诊断比值比来描述诊断特性。

结果

参与者的平均年龄为59岁[52-87岁]。LUTS-V与国际前列腺症状评分之间存在显著相关性(r=0.72,p<0.0001)。Bland-Altman分析表明两份问卷之间具有良好的一致性(偏差=5.6%)。LUTS-V在检测最严重病例方面表现出优异的诊断准确性,ROC曲线下面积为83%[78-87%],95%置信区间,p<0.001)。LUTS-V>4是最佳阈值,敏感性为74%,特异性为78%。

结论

LUTS-V是一种简单的自我管理工具,具有显著的鉴别能力,可识别中度至重度下尿路症状的患者,可能是诊断和随访有尿路症状男性的有用工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b98f/7993949/a27f70ece5b9/1677-6119-ibju-47-03-0525-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b98f/7993949/fac747c6be6a/1677-6119-ibju-47-03-0525-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b98f/7993949/ebcba2d0a48c/1677-6119-ibju-47-03-0525-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b98f/7993949/a27f70ece5b9/1677-6119-ibju-47-03-0525-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b98f/7993949/fac747c6be6a/1677-6119-ibju-47-03-0525-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b98f/7993949/ebcba2d0a48c/1677-6119-ibju-47-03-0525-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b98f/7993949/a27f70ece5b9/1677-6119-ibju-47-03-0525-gf03.jpg

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本文引用的文献

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Impact of LUTS on treatment-related behaviors and quality of life: A population-based study in Brazil.下尿路症状对治疗相关行为和生活质量的影响:巴西的一项基于人群的研究。
Neurourol Urodyn. 2019 Aug;38(6):1579-1587. doi: 10.1002/nau.24004. Epub 2019 Apr 29.
2
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Presse Med. 2018 Jul-Aug;47(7-8 Pt 1):e91-e98. doi: 10.1016/j.lpm.2018.06.011. Epub 2018 Jul 31.
3
编者按:Luts-V:一种用于评估男性下尿路症状的新简化评分方法。
Int Braz J Urol. 2021 May-Jun;47(3):533-534. doi: 10.1590/S1677-5538.IBJU.2020.0278.1.
Use of single-question screening for erectile dysfunction: a study of at-risk Asian men in primary health care.
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Sex Health. 2018 Jul;15(4):376-378. doi: 10.1071/SH17225.
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