Przelomski M M, O'Rourke E, Grady G F, Berardi V P, Markley H G
Vernon Medical Center, Worcester, MA 01604.
Neurology. 1988 May;38(5):736-9. doi: 10.1212/wnl.38.5.736.
We studied the case records of 16 patients with eastern equine encephalitis (EEE) in Massachusetts from 1970 to 1984 and compared their presentations, courses, and outcomes with the data available from previous epidemics. In recent years, there has been a greater frequency of EEE in adults, whereas in the past it was considered a disease of children. Also, prognosis for a good functional recovery seems to be correlated with age over 40 years, a long prodromal course (5 to 7 days) of constitutional symptoms, and the absence of coma. Previous reports did not mention these significant correlations. We also stress the positive and negative diagnostic correlations, in order to distinguish between EEE and herpes simplex encephalitis.
我们研究了1970年至1984年马萨诸塞州16例东部马脑炎（EEE）患者的病例记录，并将他们的临床表现、病程和转归与以往疫情中的可用数据进行了比较。近年来，EEE在成人中的发病率更高，而过去它被认为是一种儿童疾病。此外，功能良好恢复的预后似乎与40岁以上的年龄、长达5至7天的全身症状前驱期以及无昏迷状态相关。以往的报告未提及这些显著的相关性。我们还强调了诊断的正、负相关性，以便区分EEE和单纯疱疹病毒性脑炎。
