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扩展网络分析:从精神病理学到慢性疾病。

Extended network analysis: from psychopathology to chronic illness.

机构信息

Department of Psychology, Psychological Methods, University of Amsterdam, Nieuwe Achtergracht 129B, 1018 WT, Amsterdam, The Netherlands.

Research Division, Institute of Mental Health, Singapore, Singapore.

出版信息

BMC Psychiatry. 2021 Feb 27;21(1):119. doi: 10.1186/s12888-021-03128-y.

Abstract

BACKGROUND

Understanding complex associations between psychopathology and chronic illness is instrumental in facilitating both research and treatment progress. The current study is the first and only network-based study to provide such an encompassing view of unique associations between a multitude of mental and physical health-related domains.

METHODS

The current analyses were based on the Singapore Mental Health Study, a cross-sectional study of adult Singapore residents. The study sample consisted of 6616 respondents, of which 49.8% were male and 50.2% female. A network structure was constructed to examine associations between psychopathology, alcohol use, gambling, major chronic conditions, and functioning.

RESULTS

The network structure identified what we have labeled a Cartesian graph: a network visibly split into a psychopathological domain and a physical health domain. The borders between these domains were fuzzy and bridged by various cross-domain associations, with functioning items playing an important role in bridging chronic conditions to psychopathology.

CONCLUSIONS

Current results deliver a comprehensive overview of the complex relation between psychopathology, functioning, and chronic illness, highlighting potential pathways to comorbidity.

摘要

背景

理解精神病理学和慢性疾病之间的复杂关联对于促进研究和治疗进展至关重要。本研究是第一个也是唯一一个基于网络的研究,提供了对众多心理健康和身体健康相关领域之间独特关联的全面看法。

方法

本研究分析基于新加坡精神健康研究,这是一项针对新加坡成年居民的横断面研究。研究样本包括 6616 名受访者,其中 49.8%为男性,50.2%为女性。构建了一个网络结构来研究精神病理学、酒精使用、赌博、主要慢性疾病和功能之间的关联。

结果

网络结构确定了我们称之为笛卡尔图的结构:一个明显分为精神病理学领域和身体健康领域的网络。这些领域之间的边界是模糊的,由各种跨领域的关联连接,功能项目在连接慢性疾病和精神病理学方面发挥着重要作用。

结论

目前的结果提供了精神病理学、功能和慢性疾病之间复杂关系的全面概述,突出了共病的潜在途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0692/7913444/2fe23770b547/12888_2021_3128_Fig1_HTML.jpg

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