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巨大食管裂孔疝急诊修补术后功能预后差和发病率高,无症状患者是否需要择期手术?

Do Poor Functional Outcomes and Higher Morbidity Following Emergency Repair of Giant Hiatus Hernia Warrant Elective Surgery in Asymptomatic Patients?

作者信息

Bujoreanu Iulia, Abrar Daniya, Lampridis Savvas, Date Ravindra

机构信息

General Surgery Department, Royal Preston Hospital, Preston, United Kingdom.

Thoracic Surgery Department, 424 General Military Hospital, Thessaloniki, Greece.

出版信息

Front Surg. 2021 Feb 11;8:628477. doi: 10.3389/fsurg.2021.628477. eCollection 2021.

Abstract

Patients with a giant hiatus hernia may present with acute symptoms caused by obstruction, strangulation, perforation and uncontrolled bleeding. Emergency surgical repair has been associated with significant mortality and even greater morbidity. The aim of this study is to investigate the short-term outcomes following emergency repair of giant hiatus hernias. Data were retrospectively collected for all patients who underwent emergency surgical repair of giant hiatus hernia in a university teaching hospital between 2009 and 2019. Outcomes were short-term morbidity and mortality. We also assessed the association of clinical predictor covariates, including age, ASA class and time to surgery, with risk for major morbidity. Thirty-seven patients with a median age of 68 years were identified. Following surgery, 9 patients (24.3%) developed organ dysfunction that required admission to the intensive care unit. Two patients (5.4%) underwent revision surgery and 3 (8.1%) developed pneumothorax that necessitated chest drain insertion. The commonest complication was pneumonia, which occurred in 13 patients (35.1%). Two deaths (5.4%) occurred within 30 days from surgery. Emergency repair of giant hiatus hernia is associated with high rates of major morbidity, which includes poor functional status, further interventions, repeat surgery, and admission to the intensive care unit. Larger studies are warranted for long-term follow-up to assess post-operative quality of life is needed for asymptomatic patients and for those undergoing emergency surgery.

摘要

巨大食管裂孔疝患者可能会出现由梗阻、绞窄、穿孔和难以控制的出血引起的急性症状。急诊手术修复的死亡率较高,发病率甚至更高。本研究的目的是调查巨大食管裂孔疝急诊修复后的短期结果。回顾性收集了2009年至2019年期间在一所大学教学医院接受巨大食管裂孔疝急诊手术修复的所有患者的数据。结果指标为短期发病率和死亡率。我们还评估了包括年龄、美国麻醉医师协会(ASA)分级和手术时间在内的临床预测协变量与严重发病风险之间的关联。共确定了37例患者,中位年龄为68岁。术后,9例患者(24.3%)出现器官功能障碍,需要入住重症监护病房。2例患者(5.4%)接受了再次手术,3例患者(8.1%)发生气胸,需要插入胸腔引流管。最常见的并发症是肺炎,13例患者(35.1%)发生肺炎。2例患者(5.4%)在术后30天内死亡。巨大食管裂孔疝的急诊修复与高严重发病率相关,包括功能状态差、进一步干预、再次手术和入住重症监护病房。需要进行更大规模的研究进行长期随访,以评估无症状患者和接受急诊手术患者的术后生活质量。

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