Horton-French Kahlea, Dunlop Eleanor, Lucas Robyn M, Pereira Gavin, Black Lucinda J
Curtin School of Population Health, Curtin University, Bentley, WA, Australia.
National Centre for Epidemiology and Population Health, Research School of Population Health, Australian National University, Acton, ACT, Australia.
Eur J Clin Nutr. 2021 Nov;75(11):1627-1636. doi: 10.1038/s41430-021-00880-y. Epub 2021 Mar 1.
BACKGROUND/OBJECTIVES: Vitamin D deficiency is a public health concern worldwide. Maintaining vitamin D sufficiency during growth periods is essential. We aimed to determine the prevalence and predictors of vitamin D deficiency in Australian adolescents and young adults.
SUBJECT/METHODS: We used data from adolescents (12-17 years, n = 692) and young adults (18-24 years, n = 400) who participated in the nationally representative 2011-2013 Australian Health Survey. Serum 25-hydroxyvitamin D concentrations were measured using a method certified to international standards, with prevalence reported for <50 (vitamin D deficiency), 50-<75, ≥75 and >125 nmol/L. Independent predictors of vitamin D deficiency were determined using a survey-weighted Poisson regression model.
Overall, 17% of adolescents and 32% of young adults were vitamin D deficient. In models adjusted for sex, age, region of birth, socioeconomic status, BMI and season (and education, smoking status and physical activity in young adults only), the prevalence ratio (PR) for vitamin D deficiency was more than double in participants born outside Australia (adolescents: PR 2.46; 95% confidence interval (CI) = 1.59, 3.81; young adults: PR 2.12; 95% CI = 1.46, 3.07), and also varied by season (adolescents: spring vs summer PR 2.47; 95% CI = 1.22, 5.01 and winter vs summer PR 2.01; 95% CI = 1.03, 3.92; young adults: winter vs summer; PR 3.32; 95% CI = 1.69, 6.53). Other predictors of vitamin D deficiency were overweight compared with healthy weight (adolescents) and lower physical activity (young adults).
Strategies based on safe sun exposure and dietary approaches are needed to achieve and maintain adequate vitamin D status, particularly in young adults.
背景/目的:维生素D缺乏是一个全球性的公共卫生问题。在生长阶段维持充足的维生素D水平至关重要。我们旨在确定澳大利亚青少年和青年中维生素D缺乏的患病率及预测因素。
对象/方法:我们使用了参与具有全国代表性的2011 - 2013年澳大利亚健康调查的青少年(12 - 17岁,n = 692)和青年(18 - 24岁,n = 400)的数据。血清25 - 羟基维生素D浓度采用符合国际标准的方法进行测量,报告了<50(维生素D缺乏)、50 - <75、≥75和>125 nmol/L的患病率。使用调查加权泊松回归模型确定维生素D缺乏的独立预测因素。
总体而言,17%的青少年和32%的青年存在维生素D缺乏。在对性别、年龄、出生地区、社会经济状况、体重指数和季节(青年中还包括教育程度、吸烟状况和身体活动)进行调整的模型中,在澳大利亚境外出生的参与者中维生素D缺乏的患病率比(PR)增加了一倍多(青少年:PR 2.46;95%置信区间(CI)= 1.59,3.81;青年:PR 2.12;95% CI = 1.46,3.07),并且也因季节而异(青少年:春季与夏季相比PR 2.47;95% CI = 1.22,5.01,冬季与夏季相比PR 2.01;95% CI = 1.03,3.92;青年:冬季与夏季相比;PR 3.32;95% CI = 1.69,6.53)。维生素D缺乏的其他预测因素包括青少年中超重(与健康体重相比)和青年中较低的身体活动。
需要基于安全阳光照射和饮食方法的策略来实现和维持充足的维生素D状态,特别是在青年中。