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多巴胺与时间感知和奖励的相互依存关系。

Dopamine and the interdependency of time perception and reward.

机构信息

The Behavioural Insights Team, Suite 3, Level 13/9 Hunter St, Sydney NSW 2000, Australia.

The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Woods Basic Science Building Rm914, 725 N. Wolfe Street, Baltimore, MD 21205, USA.

出版信息

Neurosci Biobehav Rev. 2021 Jun;125:380-391. doi: 10.1016/j.neubiorev.2021.02.030. Epub 2021 Feb 27.

Abstract

Time is a fundamental dimension of our perception of the world and is therefore of critical importance to the organization of human behavior. A corpus of work - including recent optogenetic evidence - implicates striatal dopamine as a crucial factor influencing the perception of time. Another stream of literature implicates dopamine in reward and motivation processes. However, these two domains of research have remained largely separated, despite neurobiological overlap and the apothegmatic notion that "time flies when you're having fun". This article constitutes a review of the literature linking time perception and reward, including neurobiological and behavioral studies. Together, these provide compelling support for the idea that time perception and reward processing interact via a common dopaminergic mechanism.

摘要

时间是我们感知世界的基本维度,因此对人类行为的组织至关重要。包括最近的光遗传学证据在内的大量研究表明,纹状体多巴胺是影响时间感知的关键因素。另一系列文献则表明多巴胺参与了奖励和动机过程。然而,尽管神经生物学上存在重叠,而且有格言说“当你玩得开心时,时间过得飞快”,但这两个研究领域仍然基本上是分开的。本文综述了将时间感知和奖励联系起来的文献,包括神经生物学和行为学研究。这些研究共同有力地支持了这样一种观点,即时间感知和奖励处理通过共同的多巴胺机制相互作用。

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