Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj.
Drug & Pharmaceutical Affairs, Riyadh First Health Cluster (C1) at Ministry of Health, Riyadh.
Medicine (Baltimore). 2021 Mar 5;100(9):e24956. doi: 10.1097/MD.0000000000024956.
Due to the diversity of reports and on the rates of medications errors (MEs) in Saudi Arabia, we performed the first meta-analysis to determine the rate of medications errors in Saudi Arabia using meta-analysis in the hospital settings.
We conducted a systematic literature search through August 2019 using PubMed, EMBASE, CINAHL, PsycINFO, and Google Scholar to identify all observational studies conducted in hospital settings in Saudi Arabia that reported the rate of MEs. A random-effects models were used to calculate overall MEs, as well as prescribing, dispensing, and administration error rates. The I2 statistics were used to analyze heterogeneity.
Sixteen articles were included in this search. The total incidence of MEs in Saudi Arabia hospitals was estimated at 44.4%. Prescribing errors, dispensing errors, and adminstration errors incidents represent 40.2%, 28.2%, and 34.5% out of the total number of reported MEs, respectively. However, between-study heterogeneity was also generally found to be >90% (I-squared statistic).
This study demonstrates the MEs common in health facilities. Additional efforts in the field are needed to improve medication management systems in order to prevent patient harm incidents.
由于沙特阿拉伯关于药物错误（MEs）的报告存在多样性，我们进行了首次荟萃分析，旨在使用医院环境中的荟萃分析来确定沙特阿拉伯的药物错误率。
我们通过 PubMed、EMBASE、CINAHL、PsycINFO 和 Google Scholar 进行了系统的文献检索，以确定在沙特阿拉伯的医院环境中进行的所有报告药物错误率的观察性研究。使用随机效应模型计算总体药物错误率，以及处方、配药和给药错误率。使用 I2 统计量分析异质性。
本搜索共纳入 16 篇文章。沙特阿拉伯医院的药物错误总发生率估计为 44.4%。在报告的所有药物错误中，处方错误、配药错误和给药错误分别占 40.2%、28.2%和 34.5%。然而，研究间的异质性通常也>90%（I 平方统计量）。
本研究表明医疗机构中存在常见的药物错误。需要在该领域做出更多努力，以改善药物管理系统，防止患者伤害事件的发生。
