Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.
MARCH Centre, London School of Hygiene & Tropical Medicine, London, UK.
BMJ Glob Health. 2021 Mar;6(3). doi: 10.1136/bmjgh-2020-002452.
Improvements in maternal and infant health outcomes are policy priorities in Kenya. Achieving these outcomes depends on early identification of pregnancy and quality of primary healthcare. Quality improvement interventions have been shown to contribute to increases in identification, referral and follow-up of pregnant women by community health workers. In this study, we evaluate the cost-effectiveness of using quality improvement at community level to reduce maternal and infant mortality in Kenya.
We estimated the cost-effectiveness of quality improvement compared with standard of care treatment for antenatal and delivering mothers using a decision tree model and taking a health system perspective. We used both process (antenatal initiation in first trimester and skilled delivery) and health outcomes (maternal and infant deaths averted, as well as disability-adjusted life years (DALYs)) as our effectiveness measures and actual implementation costs, discounting costs only. We conducted deterministic and probabilistic sensitivity analyses.
We found that the community quality improvement intervention was more cost-effective compared with standard community healthcare, with incremental cost per DALY averted of $249 under the deterministic analysis and 76% likelihood of cost-effectiveness under the probabilistic sensitivity analysis using a standard threshold. The deterministic estimate of incremental cost per additional skilled delivery was US$10, per additional early antenatal care presentation US$155, per maternal death averted US$5654 and per infant death averted US$37 536 (2017 dollars).
This analysis shows that the community quality improvement intervention was cost-effective compared with the standard community healthcare in Kenya due to improvements in antenatal care uptake and skilled delivery. It is likely that quality improvement interventions are a good investment and may also yield benefits in other health areas.
改善母婴健康结果是肯尼亚的政策重点。实现这些结果取决于早期发现妊娠和初级医疗保健的质量。质量改进干预措施已被证明有助于增加社区卫生工作者对孕妇的识别、转介和随访。在这项研究中,我们评估了在社区一级使用质量改进来降低肯尼亚母婴死亡率的成本效益。
我们使用决策树模型并从卫生系统的角度,评估了质量改进与标准护理治疗产前和分娩母亲的成本效益。我们使用了过程(孕早期开始的产前护理和熟练分娩)和健康结果(避免的母婴死亡以及残疾调整生命年(DALY))作为我们的有效性衡量标准,并仅对实际实施成本进行了贴现。我们进行了确定性和概率敏感性分析。
我们发现,与标准社区医疗保健相比,社区质量改进干预措施更具成本效益,在确定性分析中,每避免一个 DALY 的增量成本为 249 美元,在使用标准阈值的概率敏感性分析中,有 76%的可能性具有成本效益。确定性估计的每增加一次熟练分娩的增量成本为 10 美元,每增加一次早期产前护理就诊的增量成本为 155 美元,每避免一次孕产妇死亡的增量成本为 5654 美元,每避免一次婴儿死亡的增量成本为 37536 美元(2017 年美元)。
这项分析表明,与肯尼亚的标准社区医疗保健相比,社区质量改进干预措施具有成本效益,因为它提高了产前保健的利用率和熟练分娩的水平。质量改进干预措施很可能是一项良好的投资,并且在其他卫生领域也可能产生效益。