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A randomized trial supports the recommendation to continue treatment with ACEi or ARBs during hospitalization for COVID-19.

作者信息

Volpe Massimo, Patrono Carlo

机构信息

Cardiology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.

Pharmacology, Catholic University School of Medicine, Rome, Italy and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Eur Heart J. 2021 Mar 14;42(11):1061-1062. doi: 10.1093/eurheartj/ehab106.

DOI:10.1093/eurheartj/ehab106
PMID:33659979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7989525/
Abstract
摘要

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本文引用的文献

1
Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19: A Randomized Clinical Trial.COVID-19 患者入院后停用与继续使用血管紧张素转换酶抑制剂和血管紧张素 II 受体阻滞剂对存活日数和出院日数的影响：一项随机临床试验。
JAMA. 2021 Jan 19;325(3):254-264. doi: 10.1001/jama.2020.25864.
2
Continuation versus discontinuation of renin-angiotensin system inhibitors in patients admitted to hospital with COVID-19: a prospective, randomised, open-label trial.COVID-19 患者住院期间继续或停用肾素-血管紧张素系统抑制剂：一项前瞻性、随机、开放标签试验。
Lancet Respir Med. 2021 Mar;9(3):275-284. doi: 10.1016/S2213-2600(20)30558-0. Epub 2021 Jan 7.
3
Systematic review of the role of renin-angiotensin system inhibitors in late studies on Covid-19: A new challenge overcome?关于肾素-血管紧张素系统抑制剂在新冠病毒后期研究中作用的系统综述：新的挑战是否已被克服？
Int J Cardiol. 2020 Dec 15;321:150-154. doi: 10.1016/j.ijcard.2020.07.041. Epub 2020 Jul 30.
4
Age and Multimorbidity Predict Death Among COVID-19 Patients: Results of the SARS-RAS Study of the Italian Society of Hypertension.年龄和多种合并症预测 COVID-19 患者的死亡：意大利高血压学会 SARS-RAS 研究的结果。
Hypertension. 2020 Aug;76(2):366-372. doi: 10.1161/HYPERTENSIONAHA.120.15324. Epub 2020 Jun 22.
5
Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19.肾素-血管紧张素-醛固酮系统阻滞剂与新冠病毒风险。
N Engl J Med. 2020 Jun 18;382(25):2431-2440. doi: 10.1056/NEJMoa2006923. Epub 2020 May 1.
6
Might renin-angiotensin system blockers play a role in the COVID-19 pandemic?血管紧张素转化酶抑制剂在新冠疫情中可能发挥作用？
Eur Heart J Cardiovasc Pharmacother. 2020 Jul 1;6(4):248-251. doi: 10.1093/ehjcvp/pvaa030.
7
Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19.新冠病毒病患者中的肾素-血管紧张素-醛固酮系统抑制剂
N Engl J Med. 2020 Apr 23;382(17):1653-1659. doi: 10.1056/NEJMsr2005760. Epub 2020 Mar 30.