Hancock John T, Russell Grace
Department of Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Plants (Basel). 2021 Feb 14;10(2):367. doi: 10.3390/plants10020367.
Molecular hydrogen (H) is now considered part of the suite of small molecules that can control cellular activity. As such, H has been suggested to be used in the therapy of diseases in humans and in plant science to enhance the growth and productivity of plants. Treatments of plants may involve the creation of hydrogen-rich water (HRW), which can then be applied to the foliage or roots systems of the plants. However, the molecular action of H remains elusive. It has been suggested that the presence of H may act as an antioxidant or on the antioxidant capacity of cells, perhaps through the scavenging of hydroxyl radicals. H may act through influencing heme oxygenase activity or through the interaction with reactive nitrogen species. However, controversy exists around all the mechanisms suggested. Here, the downstream mechanisms in which H may be involved are critically reviewed, with a particular emphasis on the H mitigation of stress responses. Hopefully, this review will provide insight that may inform future research in this area.
分子氢（H₂）现在被认为是能够控制细胞活动的小分子组合的一部分。因此，有人建议将H₂用于人类疾病治疗以及植物科学领域，以促进植物生长和提高产量。对植物的处理可能包括制造富氢水（HRW），然后将其施用于植物的叶片或根系。然而，H₂的分子作用仍然难以捉摸。有人认为，H₂的存在可能作为一种抗氧化剂，或者作用于细胞的抗氧化能力，可能是通过清除羟基自由基来实现。H₂可能通过影响血红素加氧酶活性或通过与活性氮物质相互作用来发挥作用。然而，围绕所有提出的机制都存在争议。在此，对H₂可能涉及的下游机制进行了批判性综述，特别强调了H₂对胁迫反应的缓解作用。希望这篇综述能提供一些见解，为该领域未来的研究提供参考。
