Torre María F, Martinez-Ferran María, Vallecillo Néstor, Jiménez Sergio L, Romero-Morales Carlos, Pareja-Galeano Helios
Faculty of Sport Sciences, University Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain.
Faculty of Biomedical and Health Sciences, University Europea de Madrid, 28670 Madrid, Spain.
Antioxidants (Basel). 2021 Feb 12;10(2):279. doi: 10.3390/antiox10020279.
Muscle damage induced by exercise may have several consequences such as delayed-onset muscle soreness, a side-effect of the release of free radicals during oxidative stress. To mitigate the oxidative stress cascade, the oral intake of antioxidants has been assessed by several research groups. This review examines whether supplementation with vitamin C and/or vitamin E is able to prevent or attenuate delayed-onset muscle soreness after eccentric exercise. The PubMed, Web of Science, Medline, and Embase databases were searched to identify studies meeting the inclusion criteria: primary randomized control trials, healthy male and female participants aged 16-80 years, and an intervention consisting of the intake of vitamin C and/or vitamin E without other supplements plus a controlled eccentric exercise regimen. Further requirements were the measurement of muscle soreness or markers of delayed-onset muscle soreness. All original full-text articles in English or translated into English published from January 2000 to June 2020 were considered for this review. Fourteen studies were finally identified, including 280 participants, 230 men, and 50 women aged 16-30 years. All participants were healthy individuals with different starting levels of physical activity. Supplementation was acute in two studies and chronic in 12, and its consisted of vitamin C in eight studies, vitamin E in two studies, and both in four studies. Only in 3 of the 14 studies was muscle soreness found to be significantly reduced in response to vitamin C and/or vitamin E supplementation at all time points when compared to the placebo group. Despite some studies showing the beneficial effects of chronic supplementation with these vitamins on muscle soreness manifesting 24-72 h after eccentric exercise, the evidence is so far insufficient to confirm that the intake of antioxidant vitamins is able to minimize delayed-onset muscle soreness in this context.
运动引起的肌肉损伤可能会产生多种后果，如延迟性肌肉酸痛，这是氧化应激过程中自由基释放的副作用。为了减轻氧化应激级联反应，多个研究小组对口服抗氧化剂进行了评估。本综述探讨补充维生素C和/或维生素E是否能够预防或减轻离心运动后的延迟性肌肉酸痛。检索了PubMed、科学网、Medline和Embase数据库，以确定符合纳入标准的研究：主要随机对照试验、年龄在16 - 80岁的健康男性和女性参与者，以及由摄入维生素C和/或维生素E（无其他补充剂）加受控离心运动方案组成的干预措施。进一步的要求是测量肌肉酸痛或延迟性肌肉酸痛的标志物。本综述考虑了2000年1月至2020年6月发表的所有英文或翻译成英文的原始全文文章。最终确定了14项研究，包括280名参与者，其中230名男性和50名年龄在16 - 30岁的女性。所有参与者均为健康个体，体育活动起始水平不同。两项研究中的补充是急性的，12项是慢性的，其中八项研究补充维生素C，两项研究补充维生素E，四项研究同时补充两者。与安慰剂组相比，在14项研究中只有3项发现，在所有时间点补充维生素C和/或维生素E后，肌肉酸痛显著减轻。尽管一些研究表明，长期补充这些维生素对离心运动后24 - 72小时出现的肌肉酸痛有有益影响，但迄今为止的证据不足以证实摄入抗氧化维生素能够在此背景下将延迟性肌肉酸痛降至最低。
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