Department of Anesthesiology and Gehr Family Center for Health Systems Science & Innovation, Keck School of Medicine, University of Southern California, 2020 Zonal Avenue IRD 322, Los Angeles, CA, 90033, USA.
Department of Anesthesiology, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA, 19104, USA.
World J Surg. 2021 May;45(5):1272-1290. doi: 10.1007/s00268-021-05994-9. Epub 2021 Mar 6.
Enhanced Recovery After Surgery (ERAS) protocols reduce length of stay, complications and costs for a large number of elective surgical procedures. A similar, structured approach appears to improve outcomes, including mortality, for patients undergoing high-risk emergency general surgery, and specifically emergency laparotomy. These are the first consensus guidelines for optimal care of these patients using an ERAS approach.
Experts in aspects of management of the high-risk and emergency general surgical patient were invited to contribute by the International ERAS® Society. Pubmed, Cochrane, Embase, and MEDLINE database searches on English language publications were performed for ERAS elements and relevant specific topics. Studies on each item were selected with particular attention to randomized controlled trials, systematic reviews, meta-analyses and large cohort studies, and reviewed and graded using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Recommendations were made on the best level of evidence, or extrapolation from studies on non-emergency patients when appropriate. The Delphi method was used to validate final recommendations. The guideline has been divided into two parts: Part 1-Preoperative Care and Part 2-Intraoperative and Postoperative management. This paper provides guidelines for Part 1.
Twelve components of preoperative care were considered. Consensus was reached after three rounds.
These guidelines are based on the best available evidence for an ERAS approach to patients undergoing emergency laparotomy. Initial management is particularly important for patients with sepsis and physiological derangement. These guidelines should be used to improve outcomes for these high-risk patients.
加速康复外科(ERAS)方案可减少大量择期手术的住院时间、并发症和费用。类似的结构化方法似乎也可以改善高危急诊普通外科患者的结局,包括死亡率,特别是急诊剖腹手术。这是首次使用 ERAS 方法为这些患者提供最佳护理的共识指南。
国际 ERAS®学会邀请了管理高危和急诊普通外科患者各方面的专家参与。对英文文献进行了 Pubmed、Cochrane、Embase 和 MEDLINE 数据库检索,以查找 ERAS 要素和相关专题。对每项研究进行了选择,特别注意随机对照试验、系统评价、荟萃分析和大队列研究,并使用推荐评估、制定与评价(GRADE)系统进行了审查和分级。在适当情况下,根据非急诊患者的研究进行了最佳证据或外推的推荐。采用 Delphi 方法对最终建议进行了验证。本指南分为两部分:第 1 部分-术前护理和第 2 部分-术中及术后管理。本文提供了第 1 部分的指南。
考虑了术前护理的 12 个组成部分。经过三轮投票达成了共识。
这些指南是基于 ERAS 方法用于接受急诊剖腹手术患者的最佳现有证据制定的。对于脓毒症和生理紊乱的患者,初始管理尤为重要。这些指南应有助于改善这些高危患者的结局。