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新冠疫情时代的胰腺癌:两害相权,何者为轻?

Pancreatic cancer in the era of COVID-19 pandemic: Which one is the lesser of two evils?

作者信息

Moslim Maitham A, Hall Michael J, Meyer Joshua E, Reddy Sanjay S

机构信息

Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, United States.

Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111 , United States.

出版信息

World J Clin Oncol. 2021 Feb 24;12(2):54-60. doi: 10.5306/wjco.v12.i2.54.

Abstract

Pancreatic adenocarcinoma remains one of the deadliest malignancies affecting the older population. We are experiencing a paradigm shift in the treatment of pancreatic cancer in the era of coronavirus disease 2019 (COVID-19) pandemic. Utilizing neoadjuvant treatment and further conducting a safe surgery while protecting patients in a controlled environment can improve oncological outcomes. On the other hand, an optimal oncologic procedure performed in a hazardous setting could shorten patient survival if recovery is complicated by COVID-19 infection. We believe that oncological treatment protocols must adapt to this new health threat, and pancreatic cancer is not unique in this regard. Although survival may not be as optimistic as most other malignancies, as caregivers and researchers, we are committed to innovating and reshaping the treatment algorithms to minimize morbidity and maximize survival as caregivers and researchers.

摘要

胰腺腺癌仍然是影响老年人群的最致命恶性肿瘤之一。在2019冠状病毒病(COVID-19)大流行时代,我们正在经历胰腺癌治疗模式的转变。采用新辅助治疗并在可控环境中保护患者的同时进一步进行安全手术,可以改善肿瘤治疗效果。另一方面,如果恢复过程因COVID-19感染而复杂化,在危险环境中进行的最佳肿瘤手术可能会缩短患者生存期。我们认为肿瘤治疗方案必须适应这种新的健康威胁,在这方面胰腺癌并非特例。尽管生存率可能不像大多数其他恶性肿瘤那样乐观,但作为护理人员和研究人员,我们致力于创新和重塑治疗算法,以尽量减少发病率并最大化生存率。

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