Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand.
Ophthalmic Research Group, Optometry and Vision Science, College of Health and Life Sciences, Aston University, Birmingham, UK.
Clin Exp Optom. 2021 Nov;104(8):835-840. doi: 10.1080/08164622.2021.1887580. Epub 2021 Mar 3.
: Dry eye disease is a common chronic ocular condition, which is acknowledged to have adverse impacts on quality of life and work productivity.: The wide-reaching impacts of dry eye disease on mental health and quality of life have received growing attention in recent years. The purpose of this study was therefore to investigate the relationship between dry eye disease, self-perceived health status, and self-reported psychological stress burden.: Three hundred and twelve community residents (178 females, 134 males; mean ± SD age, 38 ± 21 years) with no major systemic, ophthalmic, or psychiatric conditions (other than dry eye disease), were recruited in a cross-sectional study. Self-perceived health status and self-reported psychological stress burden were assessed, and dry eye symptomology, ocular surface characteristics, and tear film quality were evaluated for each participant within a single clinical session, in accordance with the global consensus recommendations of the Tear Film and Ocular Surface Society Dry Eye Workshop II reports.: Multivariate regression analysis, adjusted for age, sex, ethnicity, and contact lens wear, demonstrated that improved self-perceived health status was associated with decreased odds of dry eye disease, aqueous tear deficiency and meibomian gland dysfunction (all p < 0.05). Increased self-reported psychological stress burden was positively associated with dry eye disease, aqueous tear deficiency and meibomian gland dysfunction (all p ≤ 0.01).: Dry eye disease is associated with poorer self-perceived health status and greater self-reported psychological stress burden. The findings of this study highlight the wide-reaching impacts of dry eye disease, and the importance of minimising the impacts of the condition with optimised management and actioning inter-disciplinary referral for affected patients where necessary.
干眼症是一种常见的慢性眼部疾病，它被认为对生活质量和工作生产力有不良影响。近年来，干眼症对心理健康和生活质量的广泛影响受到了越来越多的关注。因此，本研究旨在探讨干眼症、自我感知健康状况和自我报告的心理压力负担之间的关系。
在一项横断面研究中，我们招募了 312 名社区居民（178 名女性，134 名男性；平均年龄 ± 标准差为 38 ± 21 岁），他们没有重大的系统性、眼部或精神疾病（除了干眼症）。我们评估了每位参与者的自我感知健康状况和自我报告的心理压力负担，并在单次临床就诊中评估了干眼症症状、眼表面特征和泪膜质量，这符合泪膜和眼表面协会干眼症工作坊 II 报告的全球共识建议。
多元回归分析，调整了年龄、性别、种族和隐形眼镜佩戴情况，表明自我感知健康状况的改善与干眼症、水样液缺乏和睑板腺功能障碍的几率降低有关（均 p < 0.05）。自我报告的心理压力负担增加与干眼症、水样液缺乏和睑板腺功能障碍呈正相关（均 p ≤ 0.01）。
干眼症与较差的自我感知健康状况和更大的自我报告心理压力负担有关。本研究的结果强调了干眼症的广泛影响，以及通过优化管理和必要时采取跨学科转介来减轻该疾病影响的重要性。
