Migliaccio Marco Giuseppe, Di Mauro Marco, Ricciolino Riccardo, Spiniello Giorgio, Carfora Vincenzo, Verde Nicoletta, Mottola Filiberto Fausto, Coppola Nicola
Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Department of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Infect Drug Resist. 2021 Mar 5;14:895-903. doi: 10.2147/IDR.S288869. eCollection 2021.
Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.
肾损伤可能是严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的一种严重并发症，并会导致预后恶化。多种病理生理机制可导致器官损伤并损害肾功能，这证明了病毒活性及其引发的免疫反应的复杂性。我们总结了关于肾脏受累的患病率、致病途径及其管理的文献证据。
