Yamamoto Wataru, Otsuji Satoru, Takiuchi Shin, Kakishita Mikio, Shimatani Yuji, Hasegawa Katsuyuki, Ishibuchi Kasumi, Tamaru Hiroto, Ishii Rui, Yasuda Shingo, Taniguchi Yusuke, Nakabayashi Sho, Kusumoto Hirofumi, Higashino Yorihiko
Department of Cardiology, Higashi Takarazuka Satoh Hospital, Takarazuka, Japan.
J Cardiol Cases. 2020 Nov 2;23(3):119-122. doi: 10.1016/j.jccase.2020.10.009. eCollection 2021 Mar.
A 63-year-old male with a medical history of uncorrected tetralogy of Fallot (TOF) presented to our hospital due to acute myocardial infarction (AMI). Emergency coronary angiography (CAG) was performed and it showed a severe thrombotic stenosis in the middle right coronary artery (RCA) and total thrombotic occlusion of the posterior descending branch of the RCA. Subsequently, percutaneous coronary artery intervention (PCI) under the guidance of intravascular ultrasound (IVUS) was performed. He was discharged on the 14th day in stable condition. Nine months after the PCI procedure, coronary computed tomography angiography was performed for follow-up, which revealed tetralogy of Fallot and complete resolution of the thrombus and ectasic coronary artery without stenosis. When he was 70 years old, he was transferred to our hospital because of recurrent AMI. As emergency CAG showed total thrombotic occlusion of the middle RCA, IVUS-guided PCI was performed. We experienced a very rare case of AMI in an adult patient with uncorrected TOF accompanied by coronary artery ectasia (CAE). To the best of our knowledge, this is the first case of AMI in an adult patient with uncorrected TOF accompanied by CAE. < Previous studies have reported that erythrocytosis of cyanotic heart disease and coronary artery ectasia (CAE) increase the risk of acute myocardial infarction (AMI) due to coronary thrombosis. In this report, we describe a very rare AMI case in an adult patient with uncorrected tetralogy of Fallot with CAE. Erythrocytosis of cyanotic heart disease and CAE can synergistically increase the risk of coronary thrombosis and anticoagulation therapy would be effective to prevent recurrent AMI.>.
一名63岁男性,有未经矫正的法洛四联症(TOF)病史,因急性心肌梗死(AMI)入住我院。进行了急诊冠状动脉造影(CAG),结果显示右冠状动脉(RCA)中段严重血栓性狭窄,RCA后降支完全血栓性闭塞。随后,在血管内超声(IVUS)引导下进行了经皮冠状动脉介入治疗(PCI)。他于第14天病情稳定出院。PCI术后9个月,进行冠状动脉计算机断层扫描血管造影随访,结果显示法洛四联症,血栓及冠状动脉扩张消失且无狭窄。70岁时,他因复发性AMI转入我院。急诊CAG显示RCA中段完全血栓性闭塞,遂进行IVUS引导下的PCI。我们遇到了一例非常罕见的成年未矫正TOF患者伴冠状动脉扩张(CAE)并发AMI的病例。据我们所知,这是首例成年未矫正TOF患者伴CAE并发AMI的病例。<先前的研究报道,青紫型心脏病的红细胞增多症和冠状动脉扩张(CAE)会增加冠状动脉血栓形成导致急性心肌梗死(AMI)的风险。在本报告中,我们描述了一例成年未矫正法洛四联症伴CAE的非常罕见的AMI病例。青紫型心脏病的红细胞增多症和CAE可协同增加冠状动脉血栓形成的风险,抗凝治疗对预防复发性AMI有效。>