CAST-HSROC：一个用于根据分层汇总接收器操作特征模型计算诊断试验准确性汇总点的网络应用程序。
CAST-HSROC: A Web Application for Calculating the Summary Points of Diagnostic Test Accuracy From the Hierarchical Summary Receiver Operating Characteristic Model.
作者信息
Banno Masahiro, Tsujimoto Yasushi, Luo Yan, Miyakoshi Chisato, Kataoka Yuki
机构信息
Department of Psychiatry, Seichiryo Hospital, Nagoya, JPN.
Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, JPN.
出版信息
Cureus. 2021 Feb 10;13(2):e13257. doi: 10.7759/cureus.13257.
BACKGROUND
Researchers have been advised to report the point estimate of either sensitivity or specificity and its 95% credible interval (CrI) for a fixed specificity or sensitivity value in the summary of findings (SoF) table for diagnostic test accuracy (DTA) when they use the hierarchical summary receiver operating characteristic (HSROC) model. However, there is no other tool that easily calculates the statistics.
RESULTS
We developed the calculator for the summary points from the HSROC model (CAST-HSROC), a web application for calculating the statistics easily. The existing graphical user interface software such as Review Manager and MetaDTA cannot calculate the statistics. Users should check whether convergence is reached before interpreting the results.
CONCLUSIONS
CAST-HSROC can easily calculate the point estimate of either sensitivity or specificity and its 95% CrI for a fixed specificity or sensitivity value on the HSROC model. The application can help to create an SoF table for DTA when systematic reviewers or guideline developers estimate the certainty of evidence on the HSROC model.
背景
当研究人员使用分层汇总接受者操作特征（HSROC）模型时，已被建议在诊断试验准确性（DTA）的研究结果总结（SoF）表中报告固定特异性或敏感性值下敏感性或特异性的点估计及其95%可信区间（CrI）。然而，没有其他工具能轻松计算这些统计量。
结果
我们开发了HSROC模型汇总点计算器（CAST-HSROC），这是一个用于轻松计算统计量的网络应用程序。诸如Review Manager和MetaDTA等现有的图形用户界面软件无法计算这些统计量。用户在解释结果之前应检查是否已达到收敛。
结论
CAST-HSROC可以轻松计算HSROC模型上固定特异性或敏感性值下敏感性或特异性的点估计及其95%CrI。当系统评价者或指南制定者评估HSROC模型上证据的确定性时，该应用程序有助于创建DTA的SoF表。
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