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SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome.患有儿童炎症性多系统综合征的儿童体内存在SARS-CoV-2特异性IgG1/IgG3,但不存在IgM。
Pediatr Allergy Immunol. 2021 Jul;32(5):1125-1129. doi: 10.1111/pai.13504. Epub 2021 Apr 18.
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Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19).儿童多系统炎症综合征(MIS-C)和轻度及重度 2019 冠状病毒病(COVID-19)患儿的严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)抗体反应。
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PLoS One. 2022 Jan 4;17(1):e0262162. doi: 10.1371/journal.pone.0262162. eCollection 2022.
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J Glob Health. 2021 Dec 25;11:01010. doi: 10.7189/jogh.11.01010. eCollection 2021.
7
Glycosylation and Serological Reactivity of an Expression-enhanced SARS-CoV-2 Viral Spike Mimetic.表达增强型 SARS-CoV-2 病毒刺突模拟物的糖基化和血清学反应性。
J Mol Biol. 2022 Jan 30;434(2):167332. doi: 10.1016/j.jmb.2021.167332. Epub 2021 Oct 27.
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Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison.儿童多系统炎症综合征与川崎病:关键对比。
Nat Rev Rheumatol. 2021 Dec;17(12):731-748. doi: 10.1038/s41584-021-00709-9. Epub 2021 Oct 29.
9
Development of a high-sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS-CoV-2 spike glycoprotein in serum and saliva.开发一种高灵敏度 ELISA 检测血清和唾液中针对 SARS-CoV-2 刺突糖蛋白的 IgG、IgA 和 IgM 抗体。
Immunology. 2021 Sep;164(1):135-147. doi: 10.1111/imm.13349. Epub 2021 May 24.

本文引用的文献

1
Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2.58 例与 SARS-CoV-2 相关的儿童炎症性多系统综合征的临床特征。
JAMA. 2020 Jul 21;324(3):259-269. doi: 10.1001/jama.2020.10369.
2
Hyperinflammatory shock in children during COVID-19 pandemic.新冠疫情期间儿童的高炎症性休克
Lancet. 2020 May 23;395(10237):1607-1608. doi: 10.1016/S0140-6736(20)31094-1. Epub 2020 May 7.
3
Site-specific glycan analysis of the SARS-CoV-2 spike.新冠病毒刺突蛋白的糖基化位点特异性分析。
Science. 2020 Jul 17;369(6501):330-333. doi: 10.1126/science.abb9983. Epub 2020 May 4.
4
Overcoming the bottleneck to widespread testing: a rapid review of nucleic acid testing approaches for COVID-19 detection.克服广泛检测的瓶颈:对 COVID-19 检测的核酸检测方法的快速综述。
RNA. 2020 Jul;26(7):771-783. doi: 10.1261/rna.076232.120. Epub 2020 May 1.
5
Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients.新型冠状病毒肺炎患者中 SARS-CoV-2 特异性 IgM 和 IgG 反应的动力学。
Emerg Microbes Infect. 2020 Dec;9(1):940-948. doi: 10.1080/22221751.2020.1762515.
6
Complement as a target in COVID-19?补体作为 COVID-19 的靶点?
Nat Rev Immunol. 2020 Jun;20(6):343-344. doi: 10.1038/s41577-020-0320-7. Epub 2020 Apr 23.
7
COVID-19: an Immunopathological View.新型冠状病毒肺炎:免疫病理学视角
mSphere. 2020 Apr 22;5(2):e00344-20. doi: 10.1128/mSphere.00344-20.
8
Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults.系统回顾儿童 COVID-19 病例表明,其症状比成人轻,预后也更好。
Acta Paediatr. 2020 Jun;109(6):1088-1095. doi: 10.1111/apa.15270. Epub 2020 Apr 14.
9
Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention.中国2019年冠状病毒病(COVID-19)疫情的特征及重要经验教训:来自中国疾病预防控制中心72314例病例报告的总结
JAMA. 2020 Apr 7;323(13):1239-1242. doi: 10.1001/jama.2020.2648.
10
The Biology of IgG Subclasses and Their Clinical Relevance to Transplantation.IgG亚类的生物学特性及其与移植的临床相关性。
Transplantation. 2018 Jan;102(1S Suppl 1):S7-S13. doi: 10.1097/TP.0000000000001816.

SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome.

作者信息

Perez-Toledo Marisol, Faustini Sian E, Jossi Sian E, Shields Adrian M, Marcial-Juarez Edith, Kanthimathinathan Hari Krishnan, Allen Joel D, Watanabe Yasunori, Goodall Margaret, Willcox Benjamin E, Willcox Carrie R, Salim Mahboob, Wraith David C, Veenith Tonny V, Syrimi Eleni, Drayson Mark T, Jyothish Deepthi, Al-Abadi Eslam, Chikermane Ashish, Welch Steven B, Masilamani Kavitha, Hackett Scott, Crispin Max, Scholefield Barnaby R, Cunningham Adam F, Richter Alex G

机构信息

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.

Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK.

出版信息

Pediatr Allergy Immunol. 2021 Jul;32(5):1125-1129. doi: 10.1111/pai.13504. Epub 2021 Apr 18.

DOI:10.1111/pai.13504
PMID:33724541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8250256/
Abstract
摘要