Mosko S S, Dickel M J, Paul T, LaTour T, Dhillon S, Ghanim A, Sassin J F
Department of Neurology, University of California Irvine Medical Center, Orange 92668.
J Am Geriatr Soc. 1988 Jun;36(6):502-8. doi: 10.1111/j.1532-5415.1988.tb04019.x.
The elderly have a high incidence of sleep complaints. A high incidence of sleep apnea (SA) and sleep-related periodic leg movements (PLMs) is also suspected. The relationship between the incidence and severity of SA and PLMs and sleep complaints has not, however, been determined in terms of symptomatology and physiologic abnormality. In a group of 46 community resident seniors (60 to 95 years old), the incidence of SA and PLMs was correlated with subjective sleep-wake complaints. Sixty-one percent of subjects had SA and/or PLMs. Apneas/hypopneas were associated with an average oxygen desaturation of less than 5% and an average change in heart rate of less than 10 beats per minute. While subjects with SA or PLMs had clear evidence of objective sleep disturbance, only one quarter of them admitted to any subjective sleep complaints or daytime sleepiness. Furthermore, severity of SA or PLMs failed to predict sleep-wake complaints, and vice versa. This study confirms that typically mild SA and PLMs are widespread in the elderly but tend not to be manifested in sleep-wake complaints and probably go untreated as a result. Further research is needed to determine any long-term medical significance.
老年人睡眠问题的发生率很高。睡眠呼吸暂停（SA）和睡眠相关性周期性腿部运动（PLMs）的发生率也被怀疑较高。然而，SA和PLMs的发生率及严重程度与睡眠问题之间的关系，在症状学和生理异常方面尚未确定。在一组46名社区居住的老年人（60至95岁）中，SA和PLMs的发生率与主观睡眠-觉醒问题相关。61%的受试者患有SA和/或PLMs。呼吸暂停/低通气与平均氧饱和度下降小于5%以及平均心率变化小于每分钟10次相关。虽然患有SA或PLMs的受试者有客观睡眠障碍的明确证据，但其中只有四分之一的人承认有任何主观睡眠问题或日间嗜睡。此外，SA或PLMs的严重程度无法预测睡眠-觉醒问题，反之亦然。这项研究证实，典型的轻度SA和PLMs在老年人中很普遍，但往往不会在睡眠-觉醒问题中表现出来，因此可能得不到治疗。需要进一步研究以确定其任何长期的医学意义。
