School of Chemical Sciences, University of Auckland, Auckland, New Zealand.
Department of Chemical and Material Engineering, University of Auckland, Auckland, New Zealand.
Biochem Soc Trans. 2021 Apr 30;49(2):953-964. doi: 10.1042/BST20200896.
Research into the development of sustainable biomaterials is increasing in both interest and global importance due to the increasing demand for materials with decreased environmental impact. This research field utilises natural, renewable resources to develop innovative biomaterials. The development of sustainable biomaterials encompasses the entire material life cycle, from desirable traits, and environmental impact from production through to recycling or disposal. The main objective of this review is to provide a comprehensive definition of sustainable biomaterials and to give an overview of the use of natural proteins in biomaterial development. Proteins such as collagen, gelatin, keratin, and silk, are biocompatible, biodegradable, and may form materials with varying properties. Proteins, therefore, provide an intriguing source of biomaterials for numerous applications, including additive manufacturing, nanotechnology, and tissue engineering. We give an insight into current research and future directions in each of these areas, to expand knowledge on the capabilities of sustainably sourced proteins as advanced biomaterials.
由于对环境影响较小的材料的需求不断增加,可持续生物材料的开发研究在兴趣和全球重要性方面都在不断增加。这个研究领域利用天然的、可再生的资源来开发创新的生物材料。可持续生物材料的发展涵盖了整个材料生命周期,从期望的特性和生产过程中的环境影响,到回收或处置。本综述的主要目的是提供可持续生物材料的全面定义,并概述天然蛋白质在生物材料开发中的应用。胶原蛋白、明胶、角蛋白和丝等蛋白质具有生物相容性、可生物降解性,并且可以形成具有不同性质的材料。因此,蛋白质为包括增材制造、纳米技术和组织工程在内的众多应用提供了有趣的生物材料来源。我们深入探讨了这些领域当前的研究和未来的发展方向,以扩展对可持续来源的蛋白质作为先进生物材料的能力的认识。