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基于汉字与图像域神经网络方法的低剂量锥形束计算机断层扫描金属伪影减少技术

Sinogram + image domain neural network approach for metal artifact reduction in low-dose cone-beam computed tomography.

作者信息

Ketcha Michael D, Marrama Michael, Souza Andre, Uneri Ali, Wu Pengwei, Zhang Xiaoxuan, Helm Patrick A, Siewerdsen Jeffrey H

机构信息

Johns Hopkins University, Department of Biomedical Engineering, Baltimore Maryland, United States.

Medtronic, Littleton, Massachusetts, United States.

出版信息

J Med Imaging (Bellingham). 2021 Sep;8(5):052103. doi: 10.1117/1.JMI.8.5.052103. Epub 2021 Mar 13.

Abstract

Cone-beam computed tomography (CBCT) is commonly used in the operating room to evaluate the placement of surgical implants in relation to critical anatomical structures. A particularly problematic setting, however, is the imaging of metallic implants, where strong artifacts can obscure visualization of both the implant and surrounding anatomy. Such artifacts are compounded when combined with low-dose imaging techniques such as sparse-view acquisition. This work presents a dual convolutional neural network approach, one operating in the sinogram domain and one in the reconstructed image domain, that is specifically designed for the physics and setting of intraoperative CBCT to address the sources of beam hardening and sparse view sampling that contribute to metal artifacts. The networks were trained with images from cadaver scans with simulated metal hardware. The trained networks were tested on images of cadavers with surgically implanted metal hardware, and performance was compared with a method operating in the image domain alone. While both methods removed most image artifacts, superior performance was observed for the dual-convolutional neural network (CNN) approach in which beam-hardening and view sampling effects were addressed in both the sinogram and image domain. The work demonstrates an innovative approach for eliminating metal and sparsity artifacts in CBCT using a dual-CNN framework which does not require a metal segmentation.

摘要

锥形束计算机断层扫描(CBCT)常用于手术室,以评估手术植入物相对于关键解剖结构的放置情况。然而,一个特别棘手的情况是对金属植入物进行成像,在这种情况下,强烈的伪影会模糊植入物和周围解剖结构的可视化。当与低剂量成像技术(如稀疏视图采集)结合使用时,这些伪影会更加严重。这项工作提出了一种双卷积神经网络方法,一个在正弦图域运行,另一个在重建图像域运行,该方法专门针对术中CBCT的物理特性和设置进行设计,以解决导致金属伪影的束硬化和稀疏视图采样问题。这些网络使用来自带有模拟金属硬件的尸体扫描图像进行训练。将训练好的网络应用于带有手术植入金属硬件的尸体图像上进行测试,并将其性能与仅在图像域运行的方法进行比较。虽然两种方法都消除了大部分图像伪影,但在双卷积神经网络(CNN)方法中观察到了更好的性能,该方法在正弦图和图像域中都解决了束硬化和视图采样效应。这项工作展示了一种使用双CNN框架消除CBCT中金属和稀疏伪影的创新方法,该方法不需要进行金属分割。

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