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孤立性远端尺骨骨转移瘤来自肺鳞癌:一例极其罕见的病例报告。

Isolated distal ulnar bone metastasis from lung squamous cell carcinoma: an extremely rare case report.

机构信息

Department of Orthopaedics, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei City, Taiwan.

Department of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, Taipei City, Taiwan.

出版信息

J Int Med Res. 2021 Mar;49(3):300060521998875. doi: 10.1177/0300060521998875.

Abstract

Bone metastases commonly occur in patients with lung cancer. However, metastasis from primary lung carcinoma to the bone below the knee and elbow is rarely encountered. We herein describe a man who developed an isolated distal ulnar bone metastasis originating from lung squamous cell carcinoma. A 68-year-old man presented to our orthopedic outpatient clinic for evaluation of a rapidly progressing tumor over his right wrist area. Tenderness with increased local temperature was noted, and the tumor was firm in consistency, oval-shaped, and 7 × 5 cm in size. Magnetic resonance imaging and radiographic imaging revealed an osteolytic tumor in his distal ulnar shaft. A 99m Tc-phosphate bone scan showed that this tumor was isolated and newly observed compared with the previous bone scan findings during initial diagnosis. Bone tumor biopsy confirmed metastatic squamous cell carcinoma. Segmental tumor resection with cementation was subsequently performed. This rare case report of an isolated ulnar metastasis includes detailed descriptions of the clinical, radiographic, and pathological features of the tumor.

摘要

肺癌患者常发生骨转移。然而,原发性肺癌向膝肘以下的骨骼转移则较为罕见。我们在此描述了 1 例肺鳞癌孤立性远端尺骨转移的病例。1 名 68 岁男性因右腕部迅速进展性肿物就诊于我院骨科门诊。触诊时局部皮温升高且压痛,肿物质地坚硬,呈卵圆形,大小约为 7×5cm。磁共振成像和 X 线片显示其远端尺骨干骺端溶骨性骨肿瘤。99mTc-磷酸盐骨扫描显示与初始诊断时的既往骨扫描结果相比,该肿瘤为孤立性、新发骨转移灶。骨肿瘤活检证实为转移性鳞状细胞癌。随后进行了节段性肿瘤切除术和骨水泥填充。该孤立性尺骨转移的罕见病例报告详细描述了肿瘤的临床、影像学和病理学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29ea/7985950/8d0dac4e5695/10.1177_0300060521998875-fig1.jpg

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