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同步发生胆囊和胆管恶性肿瘤的罕见病例中的异常胰胆管连接

Anomalous Pancreaticobiliary Duct Junction in an Unusual Case of Synchronous Gallbladder and Bile Duct Malignancy.

作者信息

Dutta Souradeep, Jain Ankit, Reddy Abhinaya, Nelamangala Ramakrishnaiah Vishnu Prasad

机构信息

Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, IND.

出版信息

Cureus. 2021 Feb 13;13(2):e13331. doi: 10.7759/cureus.13331.

DOI:10.7759/cureus.13331
PMID:33738174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7959653/
Abstract

Synchronous malignancies involving the gallbladder and the bile duct are exceedingly rare. Moreover, their association with anomalous pancreaticobiliary duct junction (APBDJ) has been reported mostly from the Far Eastern countries. Over time, many studies have suggested the definite risk of malignancy attributable to the 'carcinogenic anatomical configuration' of the long common biliopancreatic channel, allowing reflux of pancreatic juices in the biliary tract. In this report, we present a case of an elderly man from South India who was initially diagnosed with synchronous gall bladder with bile duct malignancy; the patient turned out to have an APBDJ on further evaluation.

摘要

胆囊和胆管同时发生的恶性肿瘤极为罕见。此外,它们与胰胆管异常汇合(APBDJ)的关联大多是在远东国家报道的。随着时间的推移,许多研究表明,由于长的共同胆胰管通道的“致癌解剖结构”,使得胰液反流至胆道,从而明确存在恶性肿瘤风险。在本报告中,我们介绍了一名来自印度南部的老年男性病例,该患者最初被诊断为胆囊和胆管同时发生恶性肿瘤;进一步评估发现该患者存在胰胆管异常汇合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aef4/7959653/2913b59be6b4/cureus-0013-00000013331-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aef4/7959653/fa34e33f05fa/cureus-0013-00000013331-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aef4/7959653/2913b59be6b4/cureus-0013-00000013331-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aef4/7959653/fa34e33f05fa/cureus-0013-00000013331-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aef4/7959653/2913b59be6b4/cureus-0013-00000013331-i02.jpg

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本文引用的文献

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Synchronous Gall Bladder and Bile Duct Cancer: A Short Series of Seven Cases and a Brief Review of Literature.同步性胆囊和胆管癌:七例简短病例系列及文献简要综述
J Clin Exp Hepatol. 2017 Jun;7(2):115-120. doi: 10.1016/j.jceh.2016.10.003. Epub 2016 Nov 21.
2
Classification of pancreaticobiliary maljunction and clinical features in children.儿童胰胆管合流异常的分类及临床特征。
J Hepatobiliary Pancreat Sci. 2017 Aug;24(8):449-455. doi: 10.1002/jhbp.485. Epub 2017 Jul 31.
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Pancreaticobiliary maljunction and biliary cancer.
胰胆管合流异常与胆管癌。
J Gastroenterol. 2015 Mar;50(3):273-9. doi: 10.1007/s00535-014-1015-2. Epub 2014 Nov 18.
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Japanese clinical practice guidelines for pancreaticobiliary maljunction.日本胰胆管合流异常临床实践指南。
J Gastroenterol. 2012 Jul;47(7):731-59. doi: 10.1007/s00535-012-0611-2. Epub 2012 Jun 22.
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Biliary reflux detection in anomalous union of the pancreatico-biliary duct patients.胆胰管合流异常患者的胆汁反流检测。
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Diagnostic impact of computed tomography cholangiography and magnetic resonance cholangiopancreatography on pancreaticobiliary maljunction.计算机断层扫描胆系造影和磁共振胰胆管成像对胰胆管合流异常的诊断影响。
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HPB (Oxford). 2008;10(1):48-53. doi: 10.1080/13651820701867802.
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