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普通人群中酒精成瘾与其他精神障碍的共病情况及其对治疗的影响。

The co-occurrence of alcoholism with other psychiatric disorders in the general population and its impact on treatment.

作者信息

Helzer J E, Pryzbeck T R

机构信息

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110.

出版信息

J Stud Alcohol. 1988 May;49(3):219-24. doi: 10.15288/jsa.1988.49.219.

Abstract

It is apparent from previous studies in clinical populations that there is a high comorbidity rate between alcoholism and other psychiatric diagnoses. However, this may simply be an expression of Berkson's bias (i.e., an increased tendency for persons with multiple diagnoses to seek and receive treatment and thus fall into study populations drawn from treatment sources). In this article, we use data from the Epidemiologic Catchment Area survey to examine the comorbidity between alcohol abuse and dependence, other substances of abuse and nonsubstance psychiatric disorders in a sample of approximately 20,000 persons drawn from the general population. We also examine the effect of comorbidity on psychiatric treatment. Every one of the psychiatric diagnoses we examined was more likely to occur in alcoholics than in nonalcoholics. Associations were particularly strong with antisocial personality disorder, other substance use and mania. The association between alcoholism and depressive disorders was positive but not very strong. The presence of other illnesses increased the likelihood of utilization of treatment services by alcoholics but did not increase the likelihood that drinking problems would be communicated to a doctor. The findings confirm prior studies of comorbidity in clinical samples and suggest the need for increased vigilance toward alcoholism by physicians.

摘要

从先前针对临床人群的研究中可以明显看出,酒精中毒与其他精神疾病诊断之间的共病率很高。然而,这可能仅仅是伯克森偏差的一种表现(即,患有多种诊断的人寻求并接受治疗的倾向增加,从而进入从治疗来源抽取的研究人群)。在本文中,我们使用来自流行病学集水区调查的数据,在一个从普通人群中抽取的约20000人的样本中,研究酒精滥用和依赖、其他滥用物质与非物质性精神疾病之间的共病情况。我们还研究了共病对精神治疗的影响。我们所研究的每一种精神疾病诊断在酗酒者中比在非酗酒者中更有可能出现。与反社会人格障碍、其他物质使用和躁狂症的关联尤为强烈。酒精中毒与抑郁症之间的关联是正向的,但不是很强。其他疾病的存在增加了酗酒者使用治疗服务的可能性,但并没有增加饮酒问题被告知医生的可能性。这些发现证实了先前对临床样本中共病情况的研究,并表明医生需要对酒精中毒提高警惕。

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