Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Rescources, College of Chemical Engineering, Nanjing Forestry University, Nanjing, China.
Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Nat Commun. 2021 Mar 19;12(1):1773. doi: 10.1038/s41467-021-22061-y.
The exploration of artificial luminogens with bright emission has been fully developed with the advancement of synthetic chemistry. However, many of them face problems like weakened emission in the aggregated state as well as poor renewability and sustainability. Therefore, the development of renewable and sustainable luminogens with anti-quenching function in the solid state, as well as to unveil the key factors that influence their luminescence behavior become highly significant. Herein, a new class of natural rosin-derived luminogens with aggregation-induced emission property (AIEgens) have been facilely obtained with good biocompatibility and targeted organelle imaging capability as well as photochromic behavior in the solid state. Mechanistic study indicates that the introduction of the alicyclic moiety helps suppress the excited-state molecular motion to enhance the solid-state emission. The current work fundamentally elucidates the role of alicyclic moiety in luminogen design and practically demonstrates a new source to large-scalely obtain biocompatible AIEgens.
具有明亮发射的人工发光体的探索随着合成化学的进步而得到充分发展。然而，它们中的许多都面临着聚集态下发射减弱以及可更新性和可持续性差等问题。因此，开发可再生和可持续的具有固态抗猝灭功能的发光体，并揭示影响其发光行为的关键因素变得非常重要。在此，我们通过简便的方法获得了一类具有聚集诱导发光性质（AIEgens）的新型天然松香衍生发光体，其具有良好的生物相容性和靶向细胞器成像能力，以及固态下的光致变色行为。机理研究表明，引入脂环结构有助于抑制激发态分子运动，从而增强固态发光。目前的工作从根本上阐明了脂环结构在发光体设计中的作用，并实际展示了一种大规模获得生物相容的 AIEgens 的新来源。
