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本文引用的文献

1
Ig-responsive relapsing inflammatory syndrome following COVID-19 in a kidney transplant recipient.一名肾移植受者在感染新冠病毒后出现的免疫球蛋白反应性复发性炎症综合征。
Kidney Int. 2021 Mar;99(3):767-768. doi: 10.1016/j.kint.2020.12.027. Epub 2021 Jan 22.
2
The pediatric solid organ transplant experience with COVID-19: An initial multi-center, multi-organ case series.儿科实体器官移植患者感染 COVID-19 的经验:一项初步的多中心、多器官病例系列研究。
Pediatr Transplant. 2021 May;25(3):e13868. doi: 10.1111/petr.13868. Epub 2020 Nov 9.
3
Coronavirus Disease 2019 in Autoimmune Hepatitis: A Lesson From Immunosuppressed Patients.自身免疫性肝炎中的2019冠状病毒病:来自免疫抑制患者的教训
Hepatol Commun. 2020 Jul 8;4(9):1257-1262. doi: 10.1002/hep4.1557. eCollection 2020 Sep.
4
Modulating immunosuppression in liver transplant patients with COVID-19.调节新冠病毒肺炎肝移植患者的免疫抑制状态
Gut. 2021 Jul;70(7):1412-1414. doi: 10.1136/gutjnl-2020-322620. Epub 2020 Aug 18.
5
COVID-19-Associated Multisystem Inflammatory Syndrome in Children - United States, March-July 2020.儿童感染新冠病毒相关的炎症性多系统综合征-美国,2020 年 3 月至 7 月。
MMWR Morb Mortal Wkly Rep. 2020 Aug 14;69(32):1074-1080. doi: 10.15585/mmwr.mm6932e2.
6
American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 1.美国风湿病学会关于 SARS-CoV-2 相关儿童多系统炎症综合征和儿童 COVID-19 中超炎症的临床指导:第 1 版。
Arthritis Rheumatol. 2020 Nov;72(11):1791-1805. doi: 10.1002/art.41454. Epub 2020 Oct 3.
7
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.美国儿童和青少年中的多系统炎症综合征。
N Engl J Med. 2020 Jul 23;383(4):334-346. doi: 10.1056/NEJMoa2021680. Epub 2020 Jun 29.
8
An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study.SARS-CoV-2 疫情意大年夜利中间爆发严重川崎病样病:一项不雅察性队列研究。
Lancet. 2020 Jun 6;395(10239):1771-1778. doi: 10.1016/S0140-6736(20)31103-X. Epub 2020 May 13.
9
Mild COVID-19 in a pediatric renal transplant recipient.儿科肾移植受者的轻度 COVID-19 感染。
Am J Transplant. 2020 Oct;20(10):2942-2945. doi: 10.1111/ajt.16003. Epub 2020 Jun 8.
10
Hyperinflammatory shock in children during COVID-19 pandemic.新冠疫情期间儿童的高炎症性休克
Lancet. 2020 May 23;395(10237):1607-1608. doi: 10.1016/S0140-6736(20)31094-1. Epub 2020 May 7.

一名实体器官移植受者中与SARS-CoV-2相关的儿童多系统炎症综合征。

Multisystem inflammatory syndrome in children associated with SARS-CoV-2 in a solid organ transplant recipient.

作者信息

Petters Leanne M, Vogel Tiphanie P, Munoz Flor M, Hernandez Jose A, Koohmaraie Sarah, Nowicki Michael J, Zumbro Caleb E, Mysore Krupa R

机构信息

Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

Texas Children's Hospital, Houston, Texas.

出版信息

Am J Transplant. 2021 Jul;21(7):2596-2599. doi: 10.1111/ajt.16572. Epub 2021 Apr 2.

DOI:10.1111/ajt.16572
PMID:33754452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8250508/
Abstract

We present the case of a 3-year-old female liver transplant recipient with a history of Caroli disease who presented with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) test and was ultimately diagnosed with multisystem inflammatory syndrome in children (MIS-C) complicated by portal vein thrombosis. To the best of our knowledge, this is the first case report of MIS-C in a pediatric solid organ transplant (SOT) recipient. Based on our patient, MIS-C could be a potential complication of Coronavirus disease 2019 (COVID-19) in SOT recipients and may have a negative outcome on transplant graft function.

摘要

我们报告了一名3岁女性肝移植受者的病例,该患者有卡罗里病病史,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)逆转录聚合酶链反应(RT-PCR)检测呈阳性,最终被诊断为儿童多系统炎症综合征(MIS-C)并伴有门静脉血栓形成。据我们所知,这是首例关于儿科实体器官移植(SOT)受者发生MIS-C的病例报告。基于我们的患者情况,MIS-C可能是2019冠状病毒病(COVID-19)在SOT受者中的潜在并发症,并且可能对移植移植物功能产生负面结果。