Albert Einstein College of Medicine, Bronx, NY, USA.
Department of Neurology, Weill Cornell Medicine, 520 East 70th Street, Starr Pavilion 607, New York, NY, 10021, USA.
Curr Pain Headache Rep. 2021 Mar 24;25(5):32. doi: 10.1007/s11916-021-00944-5.
Chest pain is a very common presenting complaint among patients in the hospital, a large proportion of whom have non-cardiac chest pain (NCCP). Neurological causes of NCCP have not been previously reviewed although several causes have been identified.
Chest pain has been reported as a symptom of multiple neurological conditions such as migraine, epilepsy, and multiple sclerosis, with varying clinical presentations. The affected patients are often not formally diagnosed for long periods of time due to difficulties in recognizing the symptoms as part of neurological disease processes. This paper will briefly summarize well-known etiologies of chest pain and, then, review neurological causes of NCCP, providing an overview of current literature and possible pathophysiologic mechanisms.
胸痛是医院患者中非常常见的主诉症状，其中很大一部分为非心源性胸痛（NCCP）。尽管已经确定了一些原因，但之前尚未对 NCCP 的神经源性原因进行综述。
胸痛已被报道为多种神经系统疾病的症状，如偏头痛、癫痫和多发性硬化症，其临床表现各异。由于难以将这些症状识别为神经系统疾病过程的一部分，因此受影响的患者通常在很长一段时间内未被正式诊断。本文将简要总结胸痛的一些常见病因，然后综述 NCCP 的神经源性原因，概述当前文献和可能的病理生理机制。
