Departments of Surgery, Internal Medicine and Nutritional Sciences, University of Michigan, Ann Arbor, MI, USA.
Departments of Molecular & Integrative Physiology, and Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Nat Metab. 2021 Apr;3(4):443-445. doi: 10.1038/s42255-021-00372-0.
Standfirst: Some “species differences” between mouse and human can be diminished simply by housing mice at warmer temperatures. Failure to strategically turn up the thermostat may undermine translation of findings in mice into insights on human metabolic diseases.
一些“种属差异”,例如在老鼠和人类之间,仅仅通过将老鼠饲养在更温暖的环境中就可以减少。如果未能战略性地提高温度,可能会破坏从老鼠身上的发现到人类代谢疾病的见解的转化。