Proteome-based pathology: the next frontier in precision medicine.
作者信息
Roehrl Michael H, Roehrl Victor B, Wang Julia Y
机构信息
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY.
出版信息
Expert Rev Precis Med Drug Dev. 2021;6(1):1-4. doi: 10.1080/23808993.2021.1854611.
Abstract
摘要
相似文献
1
Proteome-based pathology: the next frontier in precision medicine.基于蛋白质组学的病理学：精准医学的下一个前沿领域。
Expert Rev Precis Med Drug Dev. 2021;6(1):1-4. doi: 10.1080/23808993.2021.1854611.
2
Advancing translational research and precision medicine with targeted proteomics.通过靶向蛋白质组学推进转化研究和精准医学。
J Proteomics. 2018 Oct 30;189:1-10. doi: 10.1016/j.jprot.2018.02.021. Epub 2018 Feb 22.
3
Personalized medicine beyond genomics: alternative futures in big data-proteomics, environtome and the social proteome.超越基因组学的个性化医疗：大数据蛋白质组学、环境组和社会蛋白质组学的未来发展方向
J Neural Transm (Vienna). 2017 Jan;124(1):25-32. doi: 10.1007/s00702-015-1489-y. Epub 2015 Dec 8.
4
Next-generation proteomics: towards an integrative view of proteome dynamics.下一代蛋白质组学：走向蛋白质组动态的综合视图。
Nat Rev Genet. 2013 Jan;14(1):35-48. doi: 10.1038/nrg3356. Epub 2012 Dec 4.
5
A Comprehensive Proteomics Analysis of the Human Iris Tissue: Ready to Embrace Postgenomics Precision Medicine in Ophthalmology?人眼虹膜组织的综合蛋白质组学分析：眼科是否准备好迎接后基因组时代的精准医学？
OMICS. 2016 Sep;20(9):510-9. doi: 10.1089/omi.2016.0100.
6
Generating Proteomic Big Data for Precision Medicine.生成精准医学用蛋白质组学大数据。
Proteomics. 2020 Nov;20(21-22):e1900358. doi: 10.1002/pmic.201900358. Epub 2020 Aug 26.
7
The Emerging Role of Proteomics in Precision Medicine: Applications in Neurodegenerative Diseases and Neurotrauma.蛋白质组学在精准医学中的新兴作用：在神经退行性疾病和神经创伤中的应用
Adv Exp Med Biol. 2017;1007:59-70. doi: 10.1007/978-3-319-60733-7_4.
8
The role of proteomics in defining autoimmunity.蛋白质组学在自身免疫定义中的作用。
Expert Rev Proteomics. 2021 Mar;18(3):177-184. doi: 10.1080/14789450.2021.1914595. Epub 2021 Apr 28.
9
Application of nanomaterials in proteomics-driven precision medicine.纳米材料在蛋白质组学驱动的精准医学中的应用。
Theranostics. 2022 Mar 6;12(6):2674-2686. doi: 10.7150/thno.64325. eCollection 2022.
10
The status of proteomics as we enter the 2020s: Towards personalised/precision medicine.进入 2020 年代后蛋白质组学的现状：迈向个体化/精准医学。
Anal Biochem. 2022 May 1;644:113840. doi: 10.1016/j.ab.2020.113840. Epub 2020 Jul 31.
引用本文的文献
1
In Situ Metal-Organic Framework Growth in Serum Encapsulates and Depletes Abundant Proteins for Integrated Plasma Proteomics.血清中原位金属有机框架生长可封装并消耗丰富蛋白质用于整合血浆蛋白质组学
ACS Nano. 2025 Apr 15;19(14):13968-13981. doi: 10.1021/acsnano.4c18028. Epub 2025 Apr 1.
2
Proteomics: Unraveling the Cross Talk Between Innate Immunity and Disease Pathophysiology, Diagnostics, and Treatment Options.蛋白质组学：揭示固有免疫与疾病病理生理学、诊断和治疗选择之间的相互作用。
Adv Exp Med Biol. 2024;1443:221-242. doi: 10.1007/978-3-031-50624-6_12.
3
The 2022 Report on the Human Proteome from the HUPO Human Proteome Project.《人类蛋白质组组织 2022 年人类蛋白质组报告》。
J Proteome Res. 2023 Apr 7;22(4):1024-1042. doi: 10.1021/acs.jproteome.2c00498. Epub 2022 Nov 1.
4
dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts.使用 FragPipe 和 DIA-NN 对低样本量进行深度蛋白质组学分析的 dia-PASEF 数据分析。
Nat Commun. 2022 Jul 8;13(1):3944. doi: 10.1038/s41467-022-31492-0.
5
Precision Medicine: An Optimal Approach to Patient Care in Renal Cell Carcinoma.精准医学：肾癌患者护理的最佳方法
Front Med (Lausanne). 2022 Jun 14;9:766869. doi: 10.3389/fmed.2022.766869. eCollection 2022.
6
Application of nanomaterials in proteomics-driven precision medicine.纳米材料在蛋白质组学驱动的精准医学中的应用。
Theranostics. 2022 Mar 6;12(6):2674-2686. doi: 10.7150/thno.64325. eCollection 2022.
7
Immunoaffinity Capillary Electrophoresis in the Era of Proteoforms, Liquid Biopsy and Preventive Medicine: A Potential Impact in the Diagnosis and Monitoring of Disease Progression.免疫亲和毛细管电泳在蛋白形式、液体活检和预防医学时代：在疾病进展的诊断和监测方面的潜在影响。
Biomolecules. 2021 Oct 1;11(10):1443. doi: 10.3390/biom11101443.
8
Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project.鉴定和分析人类蛋白质组学的进展：2021 年 HUPO 人类蛋白质组计划的指标。
J Proteome Res. 2021 Dec 3;20(12):5227-5240. doi: 10.1021/acs.jproteome.1c00590. Epub 2021 Oct 20.
9
Tissue Sampling and Homogenization in the Sub-Microliter Scale with a Nanosecond Infrared Laser (NIRL) for Mass Spectrometric Proteomics.纳秒红外激光（NIRL）在亚微升规模下进行组织取样和均质化，用于质谱蛋白质组学。
Int J Mol Sci. 2021 Oct 7;22(19):10833. doi: 10.3390/ijms221910833.
本文引用的文献
1
Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project.人类蛋白质组研究取得重大里程碑：根据 HUPO 人类蛋白质组计划，现在可可靠检测到 >90%的预测人类蛋白质。
J Proteome Res. 2020 Dec 4;19(12):4735-4746. doi: 10.1021/acs.jproteome.0c00485. Epub 2020 Oct 19.
2
Strategies to enable large-scale proteomics for reproducible research.实现大规模蛋白质组学研究可重复性的策略。
Nat Commun. 2020 Jul 30;11(1):3793. doi: 10.1038/s41467-020-17641-3.
3
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma.基于基因组与蛋白质组联合分析的肺腺癌治疗靶点研究
Cell. 2020 Jul 9;182(1):200-225.e35. doi: 10.1016/j.cell.2020.06.013.
4
Maspin as a Prognostic Marker for Early Stage Colorectal Cancer With Microsatellite Instability.Maspin作为微卫星不稳定的早期结直肠癌的预后标志物
Front Oncol. 2020 Jun 10;10:945. doi: 10.3389/fonc.2020.00945. eCollection 2020.
5
STAT1 as a potential prognosis marker for poor outcomes of early stage colorectal cancer with microsatellite instability.STAT1 作为微卫星不稳定早期结直肠癌不良预后的潜在预后标志物。
PLoS One. 2020 Apr 10;15(4):e0229252. doi: 10.1371/journal.pone.0229252. eCollection 2020.
6
Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer.脯氨酰4-羟化酶α1蛋白表达对早期结直肠癌进行风险分层。
Oncotarget. 2020 Feb 25;11(8):813-824. doi: 10.18632/oncotarget.27491.
7
Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial.尿蛋白质组学早期检测糖尿病肾病及其随后用螺内酯干预延缓进展（优先）：一项前瞻性观察研究和嵌入式随机安慰剂对照试验。
Lancet Diabetes Endocrinol. 2020 Apr;8(4):301-312. doi: 10.1016/S2213-8587(20)30026-7. Epub 2020 Mar 2.
8
The Case for Proteomics and Phospho-Proteomics in Personalized Cancer Medicine.在个性化癌症医学中蛋白质组学和磷酸化蛋白质组学的应用案例
Proteomics Clin Appl. 2019 Mar;13(2):e1800113. doi: 10.1002/prca.201800113.
9
Protein identification strategies in MALDI imaging mass spectrometry: a brief review.MALDI 成像质谱分析中的蛋白质鉴定策略：简要综述。
Curr Opin Chem Biol. 2019 Feb;48:64-72. doi: 10.1016/j.cbpa.2018.10.023. Epub 2018 Nov 23.
10
SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation.SCoPE-MS：单细胞哺乳动物细胞的质谱分析定量了细胞分化过程中的蛋白质组异质性。
Genome Biol. 2018 Oct 22;19(1):161. doi: 10.1186/s13059-018-1547-5.
Zotero 插件