职业性肺病的营养因素。
Nutritional Factors in Occupational Lung Disease.
机构信息
Division of Medical Nutrition Education, College of Allied Health Profession, University of Nebraska Medical Center, 4045 Nebraska Medicine, Omaha, NE, 68198-4045, USA.
Division of Biomedical Sciences, School of Medicine, University of California-Riverside, Riverside, CA, USA.
出版信息
Curr Allergy Asthma Rep. 2021 Mar 25;21(4):24. doi: 10.1007/s11882-021-01003-0.
PURPOSE OF REVIEW
Lung diseases such as asthma and COPD are major public health issues and related to occupational exposures. While therapies to limit the development and progression of these diseases are limited, nutrition interventions could offer potential alternatives to mediate the inflammation associated with these diseases. This is a narrative review of the current state of relevant nutrients on inflammation and respiratory outcomes associated with occupational exposures.
RECENT FINDINGS
Relevant nutrients that have been investigated in recent years include omega-3 polyunsaturated fatty acids, zinc, vitamin D, dairy products, and antioxidants. These nutrients have demonstrated the potential to prevent or modify the adverse outcomes associated with occupational exposures, primarily in preclinical studies. Current therapies for respiratory consequences associated with occupational exposures are limited; therefore, addressing strategies for reducing inflammation is important in improving quality of life and limiting health care costs. More human studies are warranted to determine the effectiveness of nutrition as an intervention.
目的综述
哮喘和 COPD 等肺部疾病是主要的公共卫生问题，与职业暴露有关。尽管限制这些疾病发展和进展的治疗方法有限，但营养干预可能提供潜在的替代方法来调节与这些疾病相关的炎症。这是一篇关于相关营养素对与职业暴露相关的炎症和呼吸结果影响的综述。
最近的发现
近年来研究过的相关营养素包括 ω-3 多不饱和脂肪酸、锌、维生素 D、乳制品和抗氧化剂。这些营养素具有预防或改变与职业暴露相关的不良后果的潜力，主要是在临床前研究中。目前治疗与职业暴露相关的呼吸后果的方法有限；因此，减少炎症的策略对于提高生活质量和限制医疗保健成本非常重要。需要更多的人体研究来确定营养作为干预措施的有效性。
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