Biostatistics Research Unit, South African Medical Research Council, Durban, South Africa. Email:
Non-communicable Diseases Research Unit, South African Medical Research Council, Durban; Department of Medicine, University of Cape Town, Cape Town, South Africa.
Cardiovasc J Afr. 2021;32(3):156-160. doi: 10.5830/CVJA-2020-045. Epub 2021 Mar 26.
South Africa is experiencing an increasing burden of cardiovascular diseases, including coronary heart disease (CHD) and stroke. We aimed to obtain overall national prevalence estimates of CHD and stroke in South Africa.
Studies conducted in South Africa were systematically reviewed from PubMed, Scopus and Web of Science from January 1990 to July 2017. Random-effects meta-analyses were conducted on the selected studies to determine the overall prevalence of CHD and stroke.
Out of 2 466 studies, only 12 covering 75 140 participants reported the national prevalence of CHD and stroke. All 12 studies estimated the national prevalence of both diseases based on self-reported disease status. The overall national prevalence was 1.29 (95% CI = 0.83; 1.75) and 4.29 (95% CI = 3.13; 5.45) for CHD and stroke, respectively. Only one study reported incidence rates so we did not perform any meta-analysis of incidence rates.
There are very few studies on national prevalence of CHD and stroke in South Africa. Well-structured registries for CHD and stroke are required to accurately identify the disease burden and enable adequate resources to be allocated for the implementation of appropriate prevention and management programmes.
南非正面临心血管疾病负担日益加重的问题，包括冠心病（CHD）和中风。我们旨在获得南非 CHD 和中风的总体国家流行率估计值。
从 1990 年 1 月至 2017 年 7 月，我们从 PubMed、Scopus 和 Web of Science 系统地检索了在南非开展的研究。对选定的研究进行了随机效应荟萃分析，以确定 CHD 和中风的总体流行率。
在 2466 项研究中，只有 12 项研究（涉及 75140 名参与者）报告了 CHD 和中风的全国流行率。所有 12 项研究均基于自我报告的疾病状况来估计这两种疾病的全国流行率。CHD 和中风的总体全国流行率分别为 1.29（95%CI=0.83；1.75）和 4.29（95%CI=3.13；5.45）。仅有一项研究报告了发病率，因此我们没有对发病率进行任何荟萃分析。
南非仅有少数关于 CHD 和中风全国流行率的研究。需要建立结构良好的 CHD 和中风登记系统，以准确识别疾病负担，并为实施适当的预防和管理计划分配足够的资源。
