针对 SARS-CoV-2 的手部和表面消毒的不同制剂的病毒杀灭效力。
Virucidal efficacy of different formulations for hand and surface disinfection targeting SARS CoV-2.
机构信息
Department Research & Scientific Services, Schülke & Mayr GmbH, Norderstedt, Germany; Faculty of Mechanical Engineering, Kiel University of Applied Sciences, Kiel, Germany.
Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
出版信息
J Hosp Infect. 2021 Jun;112:27-30. doi: 10.1016/j.jhin.2021.03.015. Epub 2021 Mar 23.
In the ongoing SARS CoV-2 pandemic, effective disinfection measures are needed, and guidance based on the methodological framework of the European Committee for Standardization (CEN) may enable the choice of effective disinfectants on an immediate basis. This study aimed to elucidate whether disinfectants claiming 'virucidal activity against enveloped viruses' as specified in the European Standard EN 14476 as well as in the German Association for the Control of Viral Diseases/Robert Koch Institute (DVV/RKI) guideline are effectively inactivating SARS-CoV-2. Two commercially available formulations for surface disinfection and one formulation for hand disinfection were studied regarding their virucidal activity. Based on the data of this study the enveloped SARS-CoV-2 is at least equally susceptible compared to the standard test virus vaccinia used in the EN 14476 and DVV/RKI guidelines. Thus, chemical disinfectants claiming 'virucidal activity against enveloped viruses' based on the EN 14476 and DVV/RKI guidelines will be an effective choice to target enveloped SARS-CoV-2 as a preventive measure.
在持续的 SARS CoV-2 大流行中，需要采取有效的消毒措施，而基于欧洲标准化委员会（CEN）方法框架的指南可以使人们能够立即选择有效的消毒剂。本研究旨在阐明声称具有“对包膜病毒的杀病毒活性”的消毒剂是否能有效灭活 SARS-CoV-2，这些消毒剂在欧洲标准 EN 14476 以及德国病毒控制协会/罗伯特·科赫研究所（DVV/RKI）指南中有规定。研究了两种市售的表面消毒制剂和一种手部消毒制剂的杀病毒活性。基于这项研究的数据，包膜 SARS-CoV-2 与 EN 14476 和 DVV/RKI 指南中使用的标准测试病毒牛痘相比至少同样易感。因此，基于 EN 14476 和 DVV/RKI 指南声称具有“对包膜病毒的杀病毒活性”的化学消毒剂将是针对包膜 SARS-CoV-2 的有效预防措施。
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